DNA Optical Detection Based on Porous Silicon Technology: from Biosensors to Biochips

DNA Optical Detection Based on Porous Silicon Technology: from Biosensors to Biochips

A photochemical functionalization process which passivates the porous silicon surface of optical biosensors has been optimized as a function of the thickness and the porosity of the devices. The surface modification has been characterized by contact angle measurements. Fluorescence measurements have...

Full description

Bibliographic Details
Main Authors: Ivo Rendina, Ilaria Rea, Lucia Rotiroti, Carmen Sanges, Annalisa Lamberti, Paolo Arcari, Luca De Stefano
Format: Article
Language:English
Published: MDPI AG 2007-02-01
Series:Sensors
Subjects:
Optical Biosensors
Porous Silicon
Biochip.
Online Access:http://www.mdpi.com/1424-8220/7/2/214/
Description
Summary:A photochemical functionalization process which passivates the porous silicon surface of optical biosensors has been optimized as a function of the thickness and the porosity of the devices. The surface modification has been characterized by contact angle measurements. Fluorescence measurements have been used to investigate the stability of the DNA single strands bound to the nanostructured material. A dose-response curve for an optical label-free biosensor in the 6-80 μM range has been realized.
ISSN:1424-8220

Similar Items