Screening of novel indole steroids as cytochrome P450 substrates in silico
In this work we describe the modeling of interactions between indole steroids and steroidogenic cytochromes P450. The highest possible affinity is expected of enzymes involved in cholesterol transformation (i. e. CYP3A4, CYP7A1, CYP11A1). In case of pregnane and estrane-converting proteins a decreas...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Belarusian |
| Published: |
Belarusian State University
2018-04-01
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| Series: | Журнал Белорусского государственного университета: Химия |
| Subjects: | |
| Online Access: | https://journals.bsu.by/index.php/chemistry/article/view/1218 |