Impact of DNA methylation on 3D genome structure

Impact of DNA methylation on 3D genome structure

Multi-layered epigenetic regulation in higher eukaryotes makes it challenging to disentangle the individual effects of modifications on chromatin structure and function. Here, the authors expressed mammalian DNA methyltransferases in yeast, which have no DNA methylation, to show that methylation has...

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Bibliographic Details
Main Authors: Diana Buitrago, Mireia Labrador, Juan Pablo Arcon, Rafael Lema, Oscar Flores, Anna Esteve-Codina, Julie Blanc, Nuria Villegas, David Bellido, Marta Gut, Pablo D. Dans, Simon C. Heath, Ivo G. Gut, Isabelle Brun Heath, Modesto Orozco
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23142-8

Internet

https://doi.org/10.1038/s41467-021-23142-8

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