Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum.
<h4>Background</h4>The study of Onchocerca volvulus has been limited by its host range, with only humans and non-human primates shown to be susceptible to the full life cycle infection. Small animal models that support the development of adult parasites have not been identified.<h4>...
Main Authors: | John B Patton, Sasisekhar Bennuru, Mark L Eberhard, Jessica A Hess, April Torigian, Sara Lustigman, Thomas B Nutman, David Abraham |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-12-01
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Series: | PLoS Neglected Tropical Diseases |
Online Access: | https://doi.org/10.1371/journal.pntd.0006977 |
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