Pharmacokinetic Interaction of Paeoniflorin and Sinomenine: Pharmacokinetic Parameters and Tissue Distribution Characteristics in Rats and Protein Binding Ability In Vitro
The root of Paeonia lactiflora and the stem of Sinomenium acutum are two herbs widely used in Chinese herbal medicine for the treatment of inflammatory and arthritic diseases. Studies on the interaction of the active constituents of these herbs, i.e., paeoniflorin and sinomenine, in pharmacokinetic...
Main Authors: | Zhong Qiu Liu, Zhi Hong Jiang, Kelvin Chan, Hua Zhou, Yuen Fan Wong, Zhao Xiang Bian, Hong Xi Xu, Liang Liu |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2005-01-01
|
Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319320778 |
Similar Items
-
Mechanism of pharmacokinetic interaction between paeoniflorin and sinomenine
by: Liu, Zhongqiu
Published: (2006) -
Pharmacokinetic study of paeoniflorin in rabbits
by: I-Ju Chen, et al.
Published: (1999) -
A review on the pharmacokinetics of paeoniflorin and its anti-inflammatory and immunomodulatory effects
by: Yan-Xi Zhou, et al.
Published: (2020-10-01) -
Comparative Pharmacokinetics Study of Sinomenine in Rats after Oral Administration of Sinomenine Monomer and Sinomenium Acutum Extract
by: Mao-Fan Zhang, et al.
Published: (2014-08-01) -
Exploratory study data for determining the adverse effects of sinomenine plus gabapentin or ligustrazine hydrochloride and the pharmacokinetic insights of sinomenine in plasma and CNS tissue
by: Tianle Gao, et al.
Published: (2019-12-01)