Preparation of hydroxy genkwanin nanosuspensions and their enhanced antitumor efficacy against breast cancer

Preparation of hydroxy genkwanin nanosuspensions and their enhanced antitumor efficacy against breast cancer

Hydroxy genkwanin (HGK), a flavonoid compound from natural resources, showed good inhibition against the growth of breast tumor cells. However, the poor solubility restricted the further study and the in vivo drug delivery of HGK. We prepared HGK nanosuspensions by antisolvent precipitation method a...

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Bibliographic Details
Main Authors: Hui Ao, Yijing Li, Haowen Li, Yian Wang, Meihua Han, Yifei Guo, Rongxing Shi, Feng Yue, Xiangtao Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Drug Delivery
Subjects:
hydroxy genkwanin
nanosuspensions
cytotoxicity
antitumor efficacy
breast cancer
Online Access:http://dx.doi.org/10.1080/10717544.2020.1770372

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