Modeling and analysis of soybean (Glycine max. L) Cu/Zn, Mn and Fe superoxide dismutases

Modeling and analysis of soybean (Glycine max. L) Cu/Zn, Mn and Fe superoxide dismutases

Superoxide dismutase (SOD, EC 1.15.1.1) is an important metal-containing antioxidant enzyme that provides the first line of defense against toxic superoxide radicals by catalyzing their dismutation to oxygen and hydrogen peroxide. SOD is classified into four metalloprotein isoforms, namely, Cu/Zn SO...

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Bibliographic Details
Main Authors: V. Ramana Gopavajhula, K. Viswanatha Chaitanya, P. Akbar Ali Khan, Jilani P. Shaik, P. Narasimha Reddy, Mohammad Alanazi
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2013-01-01
Series:Genetics and Molecular Biology
Subjects:
amino acid analysis
model evaluation
molecular modeling
phylogenetic analysis
superoxide dismutase (SOD)
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000200013
Description
Summary:Superoxide dismutase (SOD, EC 1.15.1.1) is an important metal-containing antioxidant enzyme that provides the first line of defense against toxic superoxide radicals by catalyzing their dismutation to oxygen and hydrogen peroxide. SOD is classified into four metalloprotein isoforms, namely, Cu/Zn SOD, Mn SOD, Ni SOD and Fe SOD. The structural models of soybean SOD isoforms have not yet been solved. In this study, we describe structural models for soybean Cu/Zn SOD, Mn SOD and Fe SOD and provide insights into the molecular function of this metal-binding enzyme in improving tolerance to oxidative stress in plants.
ISSN:1415-4757
1678-4685

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