Stimulated Bile Production and Outflow in the Prevention and Treatment of Acute Hepatic Failure
Objective. To employ bile stimulation as a method for preventing and treating acute hepatic failure.Materials and methods. The results of the clinical examination and treatment of 52 inpatients treated for obstructive jaundice-complicated cholelithiasis, by stimulating bile production and outflow.Re...
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Russian Academy of Medical Sciences
2006-02-01
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doaj-d6023c24f959456ca29fb59c521972b62021-07-28T21:21:46ZrusRussian Academy of Medical SciencesObŝaâ Reanimatologiâ1813-97792411-71102006-02-0121656710.15360/1813-9779-2006-1-65-671202Stimulated Bile Production and Outflow in the Prevention and Treatment of Acute Hepatic FailureR. V. Bukhov0Department of Hospital Surgery, Therapeutic Faculty, Moscow State Medical Stomatological UniversityObjective. To employ bile stimulation as a method for preventing and treating acute hepatic failure.Materials and methods. The results of the clinical examination and treatment of 52 inpatients treated for obstructive jaundice-complicated cholelithiasis, by stimulating bile production and outflow.Results. All the patients with acute hepatic failure underwent 48 endoscopic interventions (endoscopic papillosphincterotomy) and 4 choledochotomy, followed by stimulation of bile production and outflow. Enhanced bile production and outflow with adequate bile outflow into the duodenum completely evacuated gallstones from the biliary tract into the duodenum and normalized the composition of hepatic bile, which could, as a rule, get clear of the signs of hepatic failure completely within 10—12 days.Conclusion. The actual possibility exists of treating and preventing acute hepatic failure, by stimulating bile production and outflow in patients with obstructive jaundice-complicated cholelithiasis. Open-access surgery (laparotomy, choledochotomy, external choledochal drainage) is indicated when endoscopic drainage of the bilious tree is ineffective and when the clinical manifestations of hepatic failure increase in cholelithiasis.https://www.reanimatology.com/rmt/article/view/1202bile stimulationcholelithiasisbile outflow |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
R. V. Bukhov |
spellingShingle |
R. V. Bukhov Stimulated Bile Production and Outflow in the Prevention and Treatment of Acute Hepatic Failure Obŝaâ Reanimatologiâ bile stimulation cholelithiasis bile outflow |
author_facet |
R. V. Bukhov |
author_sort |
R. V. Bukhov |
title |
Stimulated Bile Production and Outflow in the Prevention and Treatment of Acute Hepatic Failure |
title_short |
Stimulated Bile Production and Outflow in the Prevention and Treatment of Acute Hepatic Failure |
title_full |
Stimulated Bile Production and Outflow in the Prevention and Treatment of Acute Hepatic Failure |
title_fullStr |
Stimulated Bile Production and Outflow in the Prevention and Treatment of Acute Hepatic Failure |
title_full_unstemmed |
Stimulated Bile Production and Outflow in the Prevention and Treatment of Acute Hepatic Failure |
title_sort |
stimulated bile production and outflow in the prevention and treatment of acute hepatic failure |
publisher |
Russian Academy of Medical Sciences |
series |
Obŝaâ Reanimatologiâ |
issn |
1813-9779 2411-7110 |
publishDate |
2006-02-01 |
description |
Objective. To employ bile stimulation as a method for preventing and treating acute hepatic failure.Materials and methods. The results of the clinical examination and treatment of 52 inpatients treated for obstructive jaundice-complicated cholelithiasis, by stimulating bile production and outflow.Results. All the patients with acute hepatic failure underwent 48 endoscopic interventions (endoscopic papillosphincterotomy) and 4 choledochotomy, followed by stimulation of bile production and outflow. Enhanced bile production and outflow with adequate bile outflow into the duodenum completely evacuated gallstones from the biliary tract into the duodenum and normalized the composition of hepatic bile, which could, as a rule, get clear of the signs of hepatic failure completely within 10—12 days.Conclusion. The actual possibility exists of treating and preventing acute hepatic failure, by stimulating bile production and outflow in patients with obstructive jaundice-complicated cholelithiasis. Open-access surgery (laparotomy, choledochotomy, external choledochal drainage) is indicated when endoscopic drainage of the bilious tree is ineffective and when the clinical manifestations of hepatic failure increase in cholelithiasis. |
topic |
bile stimulation cholelithiasis bile outflow |
url |
https://www.reanimatology.com/rmt/article/view/1202 |
work_keys_str_mv |
AT rvbukhov stimulatedbileproductionandoutflowinthepreventionandtreatmentofacutehepaticfailure |
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