Rebound inflammation after an intravitreal injection in Vogt–Koyanagi–Harada syndrome
A 43-year-old male with chronic Vogt–Koyanagi–Harada syndrome (VKH) presented with subfoveal choroidal neovascular membrane (CNVM) in the right eye with no evidence of active inflammation. He underwent intravitreal bevacizumab and dexamethasone injections. Postinjection he developed fresh keratic pr...
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Wolters Kluwer Medknow Publications
2018-01-01
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doaj-d61eddd60f244de6a13651be34c23ad42020-11-25T00:47:54ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892018-01-0166686386510.4103/ijo.IJO_1145_17Rebound inflammation after an intravitreal injection in Vogt–Koyanagi–Harada syndromeRicha RanjanManisha AgarwalA 43-year-old male with chronic Vogt–Koyanagi–Harada syndrome (VKH) presented with subfoveal choroidal neovascular membrane (CNVM) in the right eye with no evidence of active inflammation. He underwent intravitreal bevacizumab and dexamethasone injections. Postinjection he developed fresh keratic precipitates and exudative retinal detachment (RD). He received two more bevacizumab injections with oral corticosteroids and immunosuppressants causing resolution of exudative RD with scarred CNVM. We report this case to highlight that intravitreal injection may act as a trigger for rebound inflammation in VKH patients and may require anti-inflammatory drugs to be started even in the absence of an active inflammation.http://www.ijo.in/article.asp?issn=0301-4738;year=2018;volume=66;issue=6;spage=863;epage=865;aulast=RanjanChoroidal neovascular membraneexudative retinal detachmentintravitreal injectionVogt–Koyanagi–Harada syndrome |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Richa Ranjan Manisha Agarwal |
spellingShingle |
Richa Ranjan Manisha Agarwal Rebound inflammation after an intravitreal injection in Vogt–Koyanagi–Harada syndrome Indian Journal of Ophthalmology Choroidal neovascular membrane exudative retinal detachment intravitreal injection Vogt–Koyanagi–Harada syndrome |
author_facet |
Richa Ranjan Manisha Agarwal |
author_sort |
Richa Ranjan |
title |
Rebound inflammation after an intravitreal injection in Vogt–Koyanagi–Harada syndrome |
title_short |
Rebound inflammation after an intravitreal injection in Vogt–Koyanagi–Harada syndrome |
title_full |
Rebound inflammation after an intravitreal injection in Vogt–Koyanagi–Harada syndrome |
title_fullStr |
Rebound inflammation after an intravitreal injection in Vogt–Koyanagi–Harada syndrome |
title_full_unstemmed |
Rebound inflammation after an intravitreal injection in Vogt–Koyanagi–Harada syndrome |
title_sort |
rebound inflammation after an intravitreal injection in vogt–koyanagi–harada syndrome |
publisher |
Wolters Kluwer Medknow Publications |
series |
Indian Journal of Ophthalmology |
issn |
0301-4738 1998-3689 |
publishDate |
2018-01-01 |
description |
A 43-year-old male with chronic Vogt–Koyanagi–Harada syndrome (VKH) presented with subfoveal choroidal neovascular membrane (CNVM) in the right eye with no evidence of active inflammation. He underwent intravitreal bevacizumab and dexamethasone injections. Postinjection he developed fresh keratic precipitates and exudative retinal detachment (RD). He received two more bevacizumab injections with oral corticosteroids and immunosuppressants causing resolution of exudative RD with scarred CNVM. We report this case to highlight that intravitreal injection may act as a trigger for rebound inflammation in VKH patients and may require anti-inflammatory drugs to be started even in the absence of an active inflammation. |
topic |
Choroidal neovascular membrane exudative retinal detachment intravitreal injection Vogt–Koyanagi–Harada syndrome |
url |
http://www.ijo.in/article.asp?issn=0301-4738;year=2018;volume=66;issue=6;spage=863;epage=865;aulast=Ranjan |
work_keys_str_mv |
AT richaranjan reboundinflammationafteranintravitrealinjectioninvogtkoyanagiharadasyndrome AT manishaagarwal reboundinflammationafteranintravitrealinjectioninvogtkoyanagiharadasyndrome |
_version_ |
1725257984968228864 |