A Randomized Controlled Neurophysiological Study of a Chinese Chan-Based Mind-Body Intervention in Patients with Major Depressive Disorder
Our previous studies have reported the therapeutic effects of 10-session Chinese Chan-based Dejian mind-body interventions (DMBI) in reducing the intake of antidepressants, improving depressive symptoms, and enhancing the attentional abilities of patients with depression. This study aims to explore...
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Online Access: | http://dx.doi.org/10.1155/2013/812096 |
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doaj-d63948fb337b42cca030aa75f427474e2020-11-24T21:11:23ZengHindawi LimitedEvidence-Based Complementary and Alternative Medicine1741-427X1741-42882013-01-01201310.1155/2013/812096812096A Randomized Controlled Neurophysiological Study of a Chinese Chan-Based Mind-Body Intervention in Patients with Major Depressive DisorderAgnes S. Chan0Yvonne M. Y. Han1Sophia L. Sze2Queenie Y. Wong3Mei-chun Cheung4Department of Psychology, The Chinese University of Hong Kong, Shatin, Hong KongDepartment of Special Education and Counselling, The Hong Kong Institute of Education, Tai Po, Hong KongDepartment of Psychology, The Chinese University of Hong Kong, Shatin, Hong KongDivision II, Kwai Chung Hospital, Kwai Chung, Hong KongDepartment of Social Work, The Chinese University of Hong Kong, Shatin, Hong KongOur previous studies have reported the therapeutic effects of 10-session Chinese Chan-based Dejian mind-body interventions (DMBI) in reducing the intake of antidepressants, improving depressive symptoms, and enhancing the attentional abilities of patients with depression. This study aims to explore the possible neuroelectrophysiological mechanisms underlying the previously reported treatment effects of DMBI in comparison with those of cognitive behavioral therapy (CBT). Seventy-five age-, gender-, and education-matched participants with depression were randomly assigned to receive either CBT or DMBI or placed on a waitlist. Eyes-closed resting EEG data were obtained individually before and after 10 weeks. After intervention, the DMBI group demonstrated significantly enhanced frontal alpha asymmetry (an index of positive mood) and intra- and interhemispheric theta coherence in frontoposterior and posterior brain regions (an index of attention). In contrast, neither the CBT nor the waitlist group showed significant changes in EEG activity patterns. Furthermore, the asymmetry and coherence indices of the DMBI group were correlated with self-reported depression severity levels and performance on an attention test, respectively. The present findings provide support for the effects of a Chinese Chan-based mind-body intervention in fostering human brain states that can facilitate positive mood and an attentive mind.http://dx.doi.org/10.1155/2013/812096 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Agnes S. Chan Yvonne M. Y. Han Sophia L. Sze Queenie Y. Wong Mei-chun Cheung |
spellingShingle |
Agnes S. Chan Yvonne M. Y. Han Sophia L. Sze Queenie Y. Wong Mei-chun Cheung A Randomized Controlled Neurophysiological Study of a Chinese Chan-Based Mind-Body Intervention in Patients with Major Depressive Disorder Evidence-Based Complementary and Alternative Medicine |
author_facet |
Agnes S. Chan Yvonne M. Y. Han Sophia L. Sze Queenie Y. Wong Mei-chun Cheung |
author_sort |
Agnes S. Chan |
title |
A Randomized Controlled Neurophysiological Study of a Chinese Chan-Based Mind-Body Intervention in Patients with Major Depressive Disorder |
title_short |
A Randomized Controlled Neurophysiological Study of a Chinese Chan-Based Mind-Body Intervention in Patients with Major Depressive Disorder |
title_full |
A Randomized Controlled Neurophysiological Study of a Chinese Chan-Based Mind-Body Intervention in Patients with Major Depressive Disorder |
title_fullStr |
A Randomized Controlled Neurophysiological Study of a Chinese Chan-Based Mind-Body Intervention in Patients with Major Depressive Disorder |
title_full_unstemmed |
A Randomized Controlled Neurophysiological Study of a Chinese Chan-Based Mind-Body Intervention in Patients with Major Depressive Disorder |
title_sort |
randomized controlled neurophysiological study of a chinese chan-based mind-body intervention in patients with major depressive disorder |
publisher |
Hindawi Limited |
series |
Evidence-Based Complementary and Alternative Medicine |
issn |
1741-427X 1741-4288 |
publishDate |
2013-01-01 |
description |
Our previous studies have reported the therapeutic effects of 10-session Chinese Chan-based Dejian mind-body interventions (DMBI) in reducing the intake of antidepressants, improving depressive symptoms, and enhancing the attentional abilities of patients with depression. This study aims to explore the possible neuroelectrophysiological mechanisms underlying the previously reported treatment effects of DMBI in comparison with those of cognitive behavioral therapy (CBT). Seventy-five age-, gender-, and education-matched participants with depression were randomly assigned to receive either CBT or DMBI or placed on a waitlist. Eyes-closed resting EEG data were obtained individually before and after 10 weeks. After intervention, the DMBI group demonstrated significantly enhanced frontal alpha asymmetry (an index of positive mood) and intra- and interhemispheric theta coherence in frontoposterior and posterior brain regions (an index of attention). In contrast, neither the CBT nor the waitlist group showed significant changes in EEG activity patterns. Furthermore, the asymmetry and coherence indices of the DMBI group were correlated with self-reported depression severity levels and performance on an attention test, respectively. The present findings provide support for the effects of a Chinese Chan-based mind-body intervention in fostering human brain states that can facilitate positive mood and an attentive mind. |
url |
http://dx.doi.org/10.1155/2013/812096 |
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