The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling.
Pressure overload of the heart leads to cardiac remodeling that may progress into heart failure, a common, morbid and mortal condition. Increased mechanistic insight into remodeling is instrumental for development of novel heart failure treatment. Cardiac remodeling comprises cardiomyocyte hypertrop...
Main Authors: | Kine Andenæs, Ida G Lunde, Naiyereh Mohammadzadeh, Christen P Dahl, Jan Magnus Aronsen, Mari E Strand, Sheryl Palmero, Ivar Sjaastad, Geir Christensen, Kristin V T Engebretsen, Theis Tønnessen |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC6063439?pdf=render |
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