Arginase 2 Deficiency Promotes Neuroinflammation and Pain Behaviors Following Nerve Injury in Mice
Microglia, the resident macrophages, act as the first and main form of active immune defense in the central nervous system. Arginase 2 (Arg2) is an enzyme involved in L-arginine metabolism and is expressed in macrophages and nervous tissue. In this study, we determined whether the absence of Arg2 pl...
Main Authors: | Yuhua Yin, Thuỳ Linh Phạm, Juhee Shin, Nara Shin, Dong-Wook Kang, Sun Yeul Lee, Wonhyung Lee, Cuk-Seong Kim, Sang Ryong Kim, Jinpyo Hong, Dong-Woon Kim |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-01-01
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Series: | Journal of Clinical Medicine |
Subjects: | |
Online Access: | https://www.mdpi.com/2077-0383/9/2/305 |
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