Recovery of ovarian function by human embryonic stem cell-derived mesenchymal stem cells in cisplatin-induced premature ovarian failure in mice

Recovery of ovarian function by human embryonic stem cell-derived mesenchymal stem cells in cisplatin-induced premature ovarian failure in mice

Abstract Background Clinical use of mesenchymal stem cells (MSCs) requires a uniform cell population, and their harvesting is invasive and produces a limited number of cells. Human embryonic stem cell-derived MSCs (hESC-MSCs) can differentiate into three germ layers and possess immunosuppressive eff...

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Main Authors: Sook Young Yoon, Jung Ah Yoon, Mira Park, Eun-Young Shin, Sookyung Jung, Jeoung Eun Lee, Jin Hee Eum, Haengseok Song, Dong Ryul Lee, Woo Sik Lee, Sang Woo Lyu
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Stem Cell Research & Therapy
Subjects:
Human embryonic stem cell-derived MSC
Chemotherapy-induced premature ovarian failure
Recovery of ovarian function
Ovarian stromal cell apoptosis
Online Access:http://link.springer.com/article/10.1186/s13287-020-01769-6

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