Release of luminal exosomes contributes to TLR4-mediated epithelial antimicrobial defense.

Exosomes are membranous nanovesicles released by most cell types from multi-vesicular endosomes. They are speculated to transfer molecules to neighboring or distant cells and modulate many physiological and pathological procedures. Exosomes released from the gastrointestinal epithelium to the basola...

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Bibliographic Details
Main Authors: Guoku Hu, Ai-Yu Gong, Amanda L Roth, Bing Q Huang, Honorine D Ward, Guan Zhu, Nicholas F Larusso, Nancy D Hanson, Xian-Ming Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3617097?pdf=render