Natural Polyphenols for Prevention and Treatment of Cancer

There is much epidemiological evidence that a diet rich in fruits and vegetables could lower the risk of certain cancers. The effect has been attributed, in part, to natural polyphenols. Besides, numerous studies have demonstrated that natural polyphenols could be used for the prevention and treatme...

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Main Authors: Yue Zhou, Jie Zheng, Ya Li, Dong-Ping Xu, Sha Li, Yu-Ming Chen, Hua-Bin Li
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Nutrients
Subjects:
Online Access:http://www.mdpi.com/2072-6643/8/8/515
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spelling doaj-d680d7fca016482ea2ecec6b59ec176c2020-11-25T02:49:56ZengMDPI AGNutrients2072-66432016-08-018851510.3390/nu8080515nu8080515Natural Polyphenols for Prevention and Treatment of CancerYue Zhou0Jie Zheng1Ya Li2Dong-Ping Xu3Sha Li4Yu-Ming Chen5Hua-Bin Li6Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, ChinaGuangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, ChinaGuangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, ChinaGuangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, ChinaSchool of Chinese Medicine, The University of Hong Kong, Hong Kong, ChinaGuangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, ChinaGuangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, ChinaThere is much epidemiological evidence that a diet rich in fruits and vegetables could lower the risk of certain cancers. The effect has been attributed, in part, to natural polyphenols. Besides, numerous studies have demonstrated that natural polyphenols could be used for the prevention and treatment of cancer. Potential mechanisms included antioxidant, anti-inflammation as well as the modulation of multiple molecular events involved in carcinogenesis. The current review summarized the anticancer efficacy of major polyphenol classes (flavonoids, phenolic acids, lignans and stilbenes) and discussed the potential mechanisms of action, which were based on epidemiological, in vitro, in vivo and clinical studies within the past five years.http://www.mdpi.com/2072-6643/8/8/515polyphenolflavonoidanticancerantioxidantanti-inflammation
collection DOAJ
language English
format Article
sources DOAJ
author Yue Zhou
Jie Zheng
Ya Li
Dong-Ping Xu
Sha Li
Yu-Ming Chen
Hua-Bin Li
spellingShingle Yue Zhou
Jie Zheng
Ya Li
Dong-Ping Xu
Sha Li
Yu-Ming Chen
Hua-Bin Li
Natural Polyphenols for Prevention and Treatment of Cancer
Nutrients
polyphenol
flavonoid
anticancer
antioxidant
anti-inflammation
author_facet Yue Zhou
Jie Zheng
Ya Li
Dong-Ping Xu
Sha Li
Yu-Ming Chen
Hua-Bin Li
author_sort Yue Zhou
title Natural Polyphenols for Prevention and Treatment of Cancer
title_short Natural Polyphenols for Prevention and Treatment of Cancer
title_full Natural Polyphenols for Prevention and Treatment of Cancer
title_fullStr Natural Polyphenols for Prevention and Treatment of Cancer
title_full_unstemmed Natural Polyphenols for Prevention and Treatment of Cancer
title_sort natural polyphenols for prevention and treatment of cancer
publisher MDPI AG
series Nutrients
issn 2072-6643
publishDate 2016-08-01
description There is much epidemiological evidence that a diet rich in fruits and vegetables could lower the risk of certain cancers. The effect has been attributed, in part, to natural polyphenols. Besides, numerous studies have demonstrated that natural polyphenols could be used for the prevention and treatment of cancer. Potential mechanisms included antioxidant, anti-inflammation as well as the modulation of multiple molecular events involved in carcinogenesis. The current review summarized the anticancer efficacy of major polyphenol classes (flavonoids, phenolic acids, lignans and stilbenes) and discussed the potential mechanisms of action, which were based on epidemiological, in vitro, in vivo and clinical studies within the past five years.
topic polyphenol
flavonoid
anticancer
antioxidant
anti-inflammation
url http://www.mdpi.com/2072-6643/8/8/515
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