Rotavirus susceptibility of antibiotic-treated mice ascribed to diminished expression of interleukin-22.
The commensal microbiota regulates susceptibility to enteric pathogens by fine-tuning mucosal innate immune responses, but how susceptibility to enteric viruses is shaped by the microbiota remains incompletely understood. Past reports have indicated that commensal bacteria may either promote or repr...
Main Authors: | Daniel Schnepf, Pedro Hernandez, Tanel Mahlakõiv, Stefania Crotta, Meagan E Sullender, Stefan T Peterson, Annette Ohnemus, Camille Michiels, Ian Gentle, Laure Dumoutier, Celso A Reis, Andreas Diefenbach, Andreas Wack, Megan T Baldridge, Peter Staeheli |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0247738 |
Similar Items
-
Leukocyte-derived IFN-α/β and epithelial IFN-λ constitute a compartmentalized mucosal defense system that restricts enteric virus infections.
by: Tanel Mahlakõiv, et al.
Published: (2015-04-01) -
Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia.
by: Stefania Crotta, et al.
Published: (2013-01-01) -
Human but not mouse hepatocytes respond to interferon-lambda in vivo.
by: Pascale Hermant, et al.
Published: (2014-01-01) -
Norovirus interactions with the commensal microbiota.
by: Meagan E Sullender, et al.
Published: (2018-09-01) -
Microbiota-Driven Tonic Interferon Signals in Lung Stromal Cells Protect from Influenza Virus Infection
by: Konrad C. Bradley, et al.
Published: (2019-07-01)