Diet Rich in Simple Sugars Promotes Pro-Inflammatory Response via Gut Microbiota Alteration and TLR4 Signaling

Diet Rich in Simple Sugars Promotes Pro-Inflammatory Response via Gut Microbiota Alteration and TLR4 Signaling

Diet is a strong modifier of microbiome and mucosal microenvironment in the gut. Recently, components of western-type diets have been associated with metabolic and immune diseases. Here, we studied how high-sugar diet (HSD) consumption influences gut mucosal barrier and immune response under steady...

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Bibliographic Details
Main Authors: Alena Fajstova, Natalie Galanova, Stepan Coufal, Jana Malkova, Martin Kostovcik, Martina Cermakova, Helena Pelantova, Marek Kuzma, Blanka Sediva, Tomas Hudcovic, Tomas Hrncir, Helena Tlaskalova-Hogenova, Miloslav Kverka, Klara Kostovcikova
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cells
Subjects:
inflammatory bowel diseases
neutrophils
metabolites
microbiome
mucosal barrier
high-sugar diet
Online Access:https://www.mdpi.com/2073-4409/9/12/2701

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