Current status and progress in noninvasive assessment of portal pressure
Portal pressure assessment is a necessary means to diagnose portal hypertension. Currently, hepatic venous pressure gradient is considered as the diagnostic gold standard for portal hypertension. However, invasiveness is one of its most critical limitations. Therefore, a noninvasive, easy, and accur...
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| Format: | Article |
| Language: | zho |
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Editorial Department of Journal of Clinical Hepatology
2014-07-01
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| Series: | Linchuang Gandanbing Zazhi |
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| Online Access: | http://www.lcgdbzz.org/qk_content.asp?id=5954&ClassID=7149458 |
| Summary: | Portal pressure assessment is a necessary means to diagnose portal hypertension. Currently, hepatic venous pressure gradient is considered as the diagnostic gold standard for portal hypertension. However, invasiveness is one of its most critical limitations. Therefore, a noninvasive, easy, and accurate measurement of portal pressure is of significant clinical value. The current noninvasive approaches to evaluate portal pressure, including CT portography, MR portography, Doppler ultrasonography, serum markers, and liver transient elastography, are summarized. Besides, a novel noninvasive portal pressure measurement technique based on the three-dimensional (3D) blood vessel model is introduced. It is pointed out that this method allows direct noninvasive measurement of portal pressure and establishment of 3D blood vessel model, as well as the diagnosis of portal hypertension based on directly simulated pressure indicators. However, this technique is being clinically tested, and its diagnostic accuracy needs to be further confirmed by large-sample clinical trials. |
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| ISSN: | 1001-5256 1001-5256 |