Detection of drug-drug interactions by modeling interaction profile fingerprints.

Detection of drug-drug interactions by modeling interaction profile fingerprints.

Drug-drug interactions (DDIs) constitute an important problem in postmarketing pharmacovigilance and in the development of new drugs. The effectiveness or toxicity of a medication could be affected by the co-administration of other drugs that share pharmacokinetic or pharmacodynamic pathways. For th...

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Bibliographic Details
Main Authors: Santiago Vilar, Eugenio Uriarte, Lourdes Santana, Nicholas P Tatonetti, Carol Friedman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3592896?pdf=render

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