Mast cells enhance sterile inflammation in chronic nonbacterial osteomyelitis

Mast cells enhance sterile inflammation in chronic nonbacterial osteomyelitis

Chronic nonbacterial osteomyelitis (CNO) is an autoinflammatory bone disease, and patients with active or recurrent bone inflammation at multiple sites are diagnosed with chronic recurrent multifocal osteomyelitis (CRMO). The Chronic multifocal osteomyelitis (CMO) mouse model develops IL-1β-driven s...

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Bibliographic Details
Main Authors: Stephanie Young, Namit Sharma, Jae Hoon Lee, Violeta Chitu, Volker Neumeister, Elisabeth Sohr, E. Richard Stanley, Christian M. Hedrich, Andrew W. B. Craig
Format: Article
Language:English
Published: The Company of Biologists 2019-08-01
Series:Disease Models & Mechanisms
Subjects:
Autoinflammation
Chronic recurrent multifocal osteomyelitis
Cytokines
Interleukin-1β
Bone disease
CNO
Online Access:http://dmm.biologists.org/content/12/8/dmm040097

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