Effect of asbestos exposure on differentiation and function of cytotoxic T lymphocytes

Effect of asbestos exposure on differentiation and function of cytotoxic T lymphocytes

Abstract Asbestos exposure is known to cause malignant mesothelioma, which is associated with poor prognosis. We focused on and examined the effect of asbestos exposure on the differentiation and function of cytotoxic T lymphocytes (CTLs). CTLs have the ability to specifically attack tumor cells aft...

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Bibliographic Details
Main Authors: Naoko Kumagai-Takei, Yasumitsu Nishimura, Megumi Maeda, Hiroaki Hayashi, Hidenori Matsuzaki, Suni Lee, Kei Yoshitome, Tatsuo Ito, Takemi Otsuki
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Environmental Health and Preventive Medicine
Subjects:
Asbestos
Cytotoxic T lymphocytes
Granzyme B
Perforin
IFN-γ
Proliferation
Online Access:http://link.springer.com/article/10.1186/s12199-020-00900-6

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