RaGOO: fast and accurate reference-guided scaffolding of draft genomes

Abstract We present RaGOO, a reference-guided contig ordering and orienting tool that leverages the speed and sensitivity of Minimap2 to accurately achieve chromosome-scale assemblies in minutes. After the pseudomolecules are constructed, RaGOO identifies structural variants, including those spannin...

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Bibliographic Details
Main Authors: Michael Alonge, Sebastian Soyk, Srividya Ramakrishnan, Xingang Wang, Sara Goodwin, Fritz J. Sedlazeck, Zachary B. Lippman, Michael C. Schatz
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Genome Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13059-019-1829-6