Atherogenic indices in non-arteritic ischemic optic neuropathy
AIM: To evaluate the atherogenic indices and the relationship with visual acuity and bilateral sequential involvement in patients with non-arteritic ischemic optic neuropathy (NAION). METHODS: A total of 65 patients with NAION and 48 age-sex matched healthy individuals were included in this retrospe...
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doaj-d70a251d797347b9a293e77801e382162021-06-25T07:29:54ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982021-07-011471041104610.18240/ijo.2021.07.1220210712Atherogenic indices in non-arteritic ischemic optic neuropathyNurullah Kocak0Volkan Yeter1Mustafa Turunc2Merve Bayrambas3Bilge Eraydin4Inci Güngor5Nurullah Koçak. Department of Ophthalmology, Ondokuzmayıs University Hospital, Atakum 55200, Samsun, Turkey. dr.nuric@hotmail.comDepartment of Ophthalmology, Ondokuzmayıs University Hospital, Atakum 55200, Samsun, TurkeyDepartment of Ophthalmology, Ondokuzmayıs University Hospital, Atakum 55200, Samsun, TurkeyDepartment of Ophthalmology, Çankırı State Hospital, Çankırı 18100, TurkeyDepartment of Ophthalmology, Erbaa State Hospital, Tokat 60500, TurkeyDepartment of Ophthalmology, Ondokuzmayıs University Hospital, Atakum 55200, Samsun, TurkeyAIM: To evaluate the atherogenic indices and the relationship with visual acuity and bilateral sequential involvement in patients with non-arteritic ischemic optic neuropathy (NAION). METHODS: A total of 65 patients with NAION and 48 age-sex matched healthy individuals were included in this retrospective study. The demographic characteristics and laboratory findings of the patients and control subjects were obtained from the electronic medical records. The atherogenic indices were calculated using the lipid parameters. The association between visual acuity, bilateral sequential involvement, and atherogenic indices was investigated. RESULTS: The mean age was 63.8±12.5y in the NAION group and 64.7±10.1y in control group (P=0.707). Although there were no significant differences in terms of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-c) between two groups (P=0.089, 0.091), all the non-traditional serum lipid ratios were significantly higher in NAION group (P<0.05). In the NAION subgroup analysis, with visual acuity≤20/200 had higher TC/high-density lipoprotein cholesterol (HDL-c), LDL-c/HDL-c, and non-HDL-c/HDL-c values than the patients in the NAION group with visual acuity >20/200 (P=0.032, 0.025, 0.032, respectively). The values for the atherogenic indices were higher in NAION patients with bilateral sequential involvement in comparison to those with unilateral involvement (P=0.271, 0.127, 0.197, 0.128, 0.127, respectively). CONCLUSION: The study reveals a relationship between NAION and the non-traditional lipid ratios. Atherogenic indices may predict the visual loss severity and second eye involvement in patients with NAION.http://ies.ijo.cn/en_publish/2021/7/20210712.pdfatherosclerosisatherogenic indexlipid profilenon-arteritic ischemic optic neuropathysecond eye involvement |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Nurullah Kocak Volkan Yeter Mustafa Turunc Merve Bayrambas Bilge Eraydin Inci Güngor |
spellingShingle |
Nurullah Kocak Volkan Yeter Mustafa Turunc Merve Bayrambas Bilge Eraydin Inci Güngor Atherogenic indices in non-arteritic ischemic optic neuropathy International Journal of Ophthalmology atherosclerosis atherogenic index lipid profile non-arteritic ischemic optic neuropathy second eye involvement |
author_facet |
Nurullah Kocak Volkan Yeter Mustafa Turunc Merve Bayrambas Bilge Eraydin Inci Güngor |
author_sort |
Nurullah Kocak |
title |
Atherogenic indices in non-arteritic ischemic optic neuropathy |
title_short |
Atherogenic indices in non-arteritic ischemic optic neuropathy |
title_full |
Atherogenic indices in non-arteritic ischemic optic neuropathy |
title_fullStr |
Atherogenic indices in non-arteritic ischemic optic neuropathy |
title_full_unstemmed |
Atherogenic indices in non-arteritic ischemic optic neuropathy |
title_sort |
atherogenic indices in non-arteritic ischemic optic neuropathy |
publisher |
Press of International Journal of Ophthalmology (IJO PRESS) |
series |
International Journal of Ophthalmology |
issn |
2222-3959 2227-4898 |
publishDate |
2021-07-01 |
description |
AIM: To evaluate the atherogenic indices and the relationship with visual acuity and bilateral sequential involvement in patients with non-arteritic ischemic optic neuropathy (NAION). METHODS: A total of 65 patients with NAION and 48 age-sex matched healthy individuals were included in this retrospective study. The demographic characteristics and laboratory findings of the patients and control subjects were obtained from the electronic medical records. The atherogenic indices were calculated using the lipid parameters. The association between visual acuity, bilateral sequential involvement, and atherogenic indices was investigated. RESULTS: The mean age was 63.8±12.5y in the NAION group and 64.7±10.1y in control group (P=0.707). Although there were no significant differences in terms of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-c) between two groups (P=0.089, 0.091), all the non-traditional serum lipid ratios were significantly higher in NAION group (P<0.05). In the NAION subgroup analysis, with visual acuity≤20/200 had higher TC/high-density lipoprotein cholesterol (HDL-c), LDL-c/HDL-c, and non-HDL-c/HDL-c values than the patients in the NAION group with visual acuity >20/200 (P=0.032, 0.025, 0.032, respectively). The values for the atherogenic indices were higher in NAION patients with bilateral sequential involvement in comparison to those with unilateral involvement (P=0.271, 0.127, 0.197, 0.128, 0.127, respectively). CONCLUSION: The study reveals a relationship between NAION and the non-traditional lipid ratios. Atherogenic indices may predict the visual loss severity and second eye involvement in patients with NAION. |
topic |
atherosclerosis atherogenic index lipid profile non-arteritic ischemic optic neuropathy second eye involvement |
url |
http://ies.ijo.cn/en_publish/2021/7/20210712.pdf |
work_keys_str_mv |
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