Clinical peculiarities of gastrointestinal symptoms in children with food allergy
Introduction. Pediatric allergy problems are widely spread among children of almost all age groups. Number of cases with combined allergic a digestive disorders increases and study of gastrointestinal lesions in children with allergies became an urgent medical and social problem. It is based on the...
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V. N. Karazin Kharkiv National University
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doaj-d72076e985c34ebf8fce56c505343ace2020-12-14T08:14:28ZengV. N. Karazin Kharkiv National UniversityJournal of V. N. Karazin Kharkiv National University: Series Medicine2313-66932313-23962020-12-01403338https://doi.org/10.26565/2313-6693-2020-40-04Clinical peculiarities of gastrointestinal symptoms in children with food allergyYuliia Karpushenko0https://orcid.org/0000-0002-2196-8817Nataliia Pavlenko1https://orcid.org/0000-0002-8882-755XKostiantyn Voloshyn2https://orcid.org/0000-0001-8262-5159PhD, Associate Professor of the department of fundamentals of pediatrics No 2, Kharkiv National Medical UniversityPhD, Associate Professor of the department of pediatric gastroenterology and nutrition, Kharkiv Medical Academy of Postgraduate EducationPhD, Associate Professor of the department of Pediatrics No 2, V. N. Karazin Kharkiv National UniversityIntroduction. Pediatric allergy problems are widely spread among children of almost all age groups. Number of cases with combined allergic a digestive disorders increases and study of gastrointestinal lesions in children with allergies became an urgent medical and social problem. It is based on the increasing frequency of both allergy and pathology of the digestive system, increasing severity of cases and necessity to analyze type of gastrointestinal disorder in children with allergy and correlation among it. Objective. To study the clinical features of gastrointestinal symptoms in children with food allergies. Materials and methods. 169 pediatric patients 3–17 years old were examined. The main group was of 105 children with food allergies, the control group – 64 children without allergies. Verification of food allergy and pathology of the digestive system was carried out in accordance with the current protocols. All patients had skin prick tests, provocative test, determination of specific IgE. All patients were divided into 3 groups by age: 1st – 3–6 years old, 2nd – 7–11 years old, 3rd – 12–17 years old. The results were processed by the methods of variation statistics. Results. Gastrointestinal manifestations were observed in children of all age groups (59 %, 65 %, 74 %). Skin manifestations predominated in the 1st and the 3rd group. Respiratory symptoms – in groups 2 and 3. A combination (more often of skin and gastrointestinal) manifestations was found in group 3. Pain syndrome in children of the main group was characterized by moderate intensity (55.2 %), more often not associated with food intake (45.7 %), localized in the umbilical region (58 %), less often in the epigastrium (23.4 %), in 15 % there was no pain. Dyspeptic syndrome was manifested by nausea (36.2 %), decreased appetite (25.7 %) and belching (17.1 %). Dyspeptic syndrome was absent in 34.3 % of patients. The manifestations of asthenovegetative syndrome were noted in 38.1 % of children in the main group. The correlation between the type of allergen and the reason of gastrointestinal symptoms has not been identified. Conclusions. A variety of clinical manifestations of food allergy has been proven in the form of skin, gastrointestinal, respiratory symptoms and their combination. Gastrointestinal symptoms indicate the presence of functional disorders of the digestive tract. With age, the variety of food allergens increases, without qualitatively affecting the nature of gastrointestinal symptoms.https://periodicals.karazin.ua/medicine/article/view/16495childrendigestionfood allergyallergydigestive system |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Yuliia Karpushenko Nataliia Pavlenko Kostiantyn Voloshyn |
spellingShingle |
Yuliia Karpushenko Nataliia Pavlenko Kostiantyn Voloshyn Clinical peculiarities of gastrointestinal symptoms in children with food allergy Journal of V. N. Karazin Kharkiv National University: Series Medicine children digestion food allergy allergy digestive system |
author_facet |
Yuliia Karpushenko Nataliia Pavlenko Kostiantyn Voloshyn |
author_sort |
Yuliia Karpushenko |
title |
Clinical peculiarities of gastrointestinal symptoms in children with food allergy |
title_short |
Clinical peculiarities of gastrointestinal symptoms in children with food allergy |
title_full |
Clinical peculiarities of gastrointestinal symptoms in children with food allergy |
title_fullStr |
Clinical peculiarities of gastrointestinal symptoms in children with food allergy |
title_full_unstemmed |
Clinical peculiarities of gastrointestinal symptoms in children with food allergy |
title_sort |
clinical peculiarities of gastrointestinal symptoms in children with food allergy |
publisher |
V. N. Karazin Kharkiv National University |
series |
Journal of V. N. Karazin Kharkiv National University: Series Medicine |
issn |
2313-6693 2313-2396 |
publishDate |
2020-12-01 |
description |
Introduction. Pediatric allergy problems are widely spread among children of almost all age groups. Number of cases with combined allergic a digestive disorders increases and study of gastrointestinal lesions in children with allergies became an urgent medical and social problem. It is based on the increasing frequency of both allergy and pathology of the digestive system, increasing severity of cases and necessity to analyze type of gastrointestinal disorder in children with allergy and correlation among it. Objective. To study the clinical features of gastrointestinal symptoms in children with food allergies. Materials and methods. 169 pediatric patients 3–17 years old were examined. The main group was of 105 children with food allergies, the control group – 64 children without allergies. Verification of food allergy and pathology of the digestive system was carried out in accordance with the current protocols. All patients had skin prick tests, provocative test, determination of specific IgE. All patients were divided into 3 groups by age: 1st – 3–6 years old, 2nd – 7–11 years old, 3rd – 12–17 years old. The results were processed by the methods of variation statistics. Results. Gastrointestinal manifestations were observed in children of all age groups (59 %, 65 %, 74 %). Skin manifestations predominated in the 1st and the 3rd group. Respiratory symptoms – in groups 2 and 3. A combination (more often of skin and gastrointestinal) manifestations was found in group 3. Pain syndrome in children of the main group was characterized by moderate intensity (55.2 %), more often not associated with food intake (45.7 %), localized in the umbilical region (58 %), less often in the epigastrium (23.4 %), in 15 % there was no pain. Dyspeptic syndrome was manifested by nausea (36.2 %), decreased appetite (25.7 %) and belching (17.1 %). Dyspeptic syndrome was absent in 34.3 % of patients. The manifestations of asthenovegetative syndrome were noted in 38.1 % of children in the main group. The correlation between the type of allergen and the reason of gastrointestinal symptoms has not been identified. Conclusions. A variety of clinical manifestations of food allergy has been proven in the form of skin, gastrointestinal, respiratory symptoms and their combination. Gastrointestinal symptoms indicate the presence of functional disorders of the digestive tract. With age, the variety of food allergens increases, without qualitatively affecting the nature of gastrointestinal symptoms. |
topic |
children digestion food allergy allergy digestive system |
url |
https://periodicals.karazin.ua/medicine/article/view/16495 |
work_keys_str_mv |
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