Human leukocyte antigen susceptibility genes in multiple sclerosis
Multiple sclerosis (MS) is an immune ⁃ related demyelinating disease of the central nervous system. The onset age of MS is usually between 20-40 years, showing a heterogeneous clinical feature. Due to the high disability rate, MS causes a huge burden to the society. MS is a complex disease caused by...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Tianjin Huanhu Hospital
2012-04-01
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| Series: | Chinese Journal of Contemporary Neurology and Neurosurgery |
| Subjects: | |
| Online Access: | http://www.cjcnn.org/index.php/cjcnn/article/view/135 |
| Summary: | Multiple sclerosis (MS) is an immune ⁃ related demyelinating disease of the central nervous system. The onset age of MS is usually between 20-40 years, showing a heterogeneous clinical feature. Due to the high disability rate, MS causes a huge burden to the society. MS is a complex disease caused by the genetic and environmental factors, in which genetic factors play a critical role. HLA gene complex is the most important determinant in MS risk, with a risk factor rate more than 60%. HLA gene complex has been a focus in MS research worldwide.
DOI：10.3969/j.issn.1672⁃6731.2012.02.006 |
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| ISSN: | 1672-6731 |