In vitro activity of hypnophilin from Lentinus strigosus: a potential prototype for Chagas disease and leishmaniasis chemotherapy

In vitro activity of hypnophilin from Lentinus strigosus: a potential prototype for Chagas disease and leishmaniasis chemotherapy

Hypnophilin and panepoxydone, terpenoids isolated from Lentinus strigosus, have significant inhibitory activity onTrypanosoma cruzi trypanothione reductase (TR). Although they have similar TR inhibitory activity at 10 μg/mL (40.3 μM and 47.6 μM for hypnophilin and panepoxy...

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Bibliographic Details
Main Authors:	E.M. Souza-Fagundes, B.B. Cota, L.H. Rosa, A.J. Romanha, R. Corrêa-Oliveira, C.A. Rosa, C.L. Zani, A. Teixeira-Carvalho, O.A. Martins-Filho
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2010-11-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	Chagas disease Leishmaniasis Chemotherapy Immunomodulation Hypnophilin Lentinus strigosus
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010001100007

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