Renin-angiotensin and kallikrein-kinin systems in diabetic retinopathy

This brief review describes how two complex systems, the renin-angiotensin system (RAS) and the kallikrein-kinin system (KKS), affect the retina. It emphasises the important physiological actions of components of these systems, the protective effectiveness of angiotensin I converting enzyme (ACE) in...

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Bibliographic Details
Main Author: Igić Rajko
Format: Article
Language:English
Published: Medical Society of the Republic of Srpska, Banja Luka, University of Banja Luka. Faculty of Medicine 2019-01-01
Series:Scripta Medica
Subjects:
ras
kks
ace
Online Access:https://scindeks-clanci.ceon.rs/data/pdf/2490-3329/2019/2490-33291903129I.pdf
Description
Summary:This brief review describes how two complex systems, the renin-angiotensin system (RAS) and the kallikrein-kinin system (KKS), affect the retina. It emphasises the important physiological actions of components of these systems, the protective effectiveness of angiotensin I converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARB) in diabetic retinopathy and suggests as well the therapeutic possibilities for treatment of diabetic retinopathy by selective activation of bradykinin receptors (B1 and B2).
ISSN:2490-3329
2303-7954