Membrane protein Nav1.7 contributes to the persistent post-surgical pain regulated by p-p65 in dorsal root ganglion (DRG) of SMIR rats model

Membrane protein Nav1.7 contributes to the persistent post-surgical pain regulated by p-p65 in dorsal root ganglion (DRG) of SMIR rats model

Abstract Background Persistent post-surgical pain is a difficult clinical problem. In this study, we intend to explore the mechanism underlying the persistent post-surgical pain in SMIR (skin/muscle incision and retraction) rats. Methods First of all, the expression of membrane protein Nav1.7 and p-...

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Bibliographic Details
Main Authors: Zhisong Li, Yaru Li, Jing Cao, Xuemin Han, Weihua Cai, Weidong Zang, Jitian Xu, Wei Zhang
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Anesthesiology
Subjects:
Persistent post-surgical pain
Mechanical hyperalgesia
DRG
P-p65
Nav1.7
Online Access:http://link.springer.com/article/10.1186/s12871-017-0438-8

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