Activity of keloids evaluated by multimodal photoacoustic/ultrasonic imaging system
Multiple objective assessments have been used to assess the activity of keloids to compare different therapeutic regimens and facilitate the best individual treatment choice for patients, but none of them are standardized. A multimodal photoacoustic/ultrasonic (PA/US) imaging system, including photo...
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doaj-d77344ba0b8d413aa7ad0eb2ec2859f12021-09-13T04:14:08ZengElsevierPhotoacoustics2213-59792021-12-0124100302Activity of keloids evaluated by multimodal photoacoustic/ultrasonic imaging systemCheng Chen0Sirui Liu1Chenyang Zhao2Ruojiao Wang3Nanze Yu4Xiao Long5Youbin Wang6Fang Yang7Jie Sun8Zhao Ling Lu9Yu Xia10Yuxin Jiang11Meng Yang12Department of Ultrasonography, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDepartment of Ultrasonography, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDepartment of Ultrasonography, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDepartment of Ultrasonography, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDepartment of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDepartment of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDepartment of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaMindray Bio-Medical Electronics Co., Ltd., Shenzhen, ChinaMindray Bio-Medical Electronics Co., Ltd., Shenzhen, ChinaMindray North American Innovation Center, San Jose, CA, United StatesDepartment of Ultrasonography, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDepartment of Ultrasonography, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Corresponding authors at: Department of Ultrasonography, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Address: No.1, Shuaifuyuan, Dongcheng District, Beijing, China.Department of Ultrasonography, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Corresponding authors at: Department of Ultrasonography, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Address: No.1, Shuaifuyuan, Dongcheng District, Beijing, China.Multiple objective assessments have been used to assess the activity of keloids to compare different therapeutic regimens and facilitate the best individual treatment choice for patients, but none of them are standardized. A multimodal photoacoustic/ultrasonic (PA/US) imaging system, including photoacoustic imaging, elastography, ultra-micro-angiography, and conventional US technologies (gray scale US, color Doppler US, and power Doppler US), was applied to evaluate keloids by a radiologist. Growing stages were defined by patients, and Vancouver Scar Scale (VSS) was assessed by a plastic surgeon. A comprehensive model based on multimodal ultrasound parameters (poor-echo pattern, high vascular density, decreased elasticity, and low SO2 within the keloid) and VSS might be a potential indicator of active keloids, comparing with VSS alone. The multimodal PA/US imaging system could be a promising technique for keloids assessment.http://www.sciencedirect.com/science/article/pii/S2213597921000628KeloidsUltrasoundPhotoacoustic imagingVancouver Scar Scale |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Cheng Chen Sirui Liu Chenyang Zhao Ruojiao Wang Nanze Yu Xiao Long Youbin Wang Fang Yang Jie Sun Zhao Ling Lu Yu Xia Yuxin Jiang Meng Yang |
spellingShingle |
Cheng Chen Sirui Liu Chenyang Zhao Ruojiao Wang Nanze Yu Xiao Long Youbin Wang Fang Yang Jie Sun Zhao Ling Lu Yu Xia Yuxin Jiang Meng Yang Activity of keloids evaluated by multimodal photoacoustic/ultrasonic imaging system Photoacoustics Keloids Ultrasound Photoacoustic imaging Vancouver Scar Scale |
author_facet |
Cheng Chen Sirui Liu Chenyang Zhao Ruojiao Wang Nanze Yu Xiao Long Youbin Wang Fang Yang Jie Sun Zhao Ling Lu Yu Xia Yuxin Jiang Meng Yang |
author_sort |
Cheng Chen |
title |
Activity of keloids evaluated by multimodal photoacoustic/ultrasonic imaging system |
title_short |
Activity of keloids evaluated by multimodal photoacoustic/ultrasonic imaging system |
title_full |
Activity of keloids evaluated by multimodal photoacoustic/ultrasonic imaging system |
title_fullStr |
Activity of keloids evaluated by multimodal photoacoustic/ultrasonic imaging system |
title_full_unstemmed |
Activity of keloids evaluated by multimodal photoacoustic/ultrasonic imaging system |
title_sort |
activity of keloids evaluated by multimodal photoacoustic/ultrasonic imaging system |
publisher |
Elsevier |
series |
Photoacoustics |
issn |
2213-5979 |
publishDate |
2021-12-01 |
description |
Multiple objective assessments have been used to assess the activity of keloids to compare different therapeutic regimens and facilitate the best individual treatment choice for patients, but none of them are standardized. A multimodal photoacoustic/ultrasonic (PA/US) imaging system, including photoacoustic imaging, elastography, ultra-micro-angiography, and conventional US technologies (gray scale US, color Doppler US, and power Doppler US), was applied to evaluate keloids by a radiologist. Growing stages were defined by patients, and Vancouver Scar Scale (VSS) was assessed by a plastic surgeon. A comprehensive model based on multimodal ultrasound parameters (poor-echo pattern, high vascular density, decreased elasticity, and low SO2 within the keloid) and VSS might be a potential indicator of active keloids, comparing with VSS alone. The multimodal PA/US imaging system could be a promising technique for keloids assessment. |
topic |
Keloids Ultrasound Photoacoustic imaging Vancouver Scar Scale |
url |
http://www.sciencedirect.com/science/article/pii/S2213597921000628 |
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