A Longitudinal fMRI Research on Neural Plasticity and Sensory Outcome of Carpal Tunnel Syndrome

A Longitudinal fMRI Research on Neural Plasticity and Sensory Outcome of Carpal Tunnel Syndrome

Peripheral nerve compression is reported to induce cortical plasticity, which was well pictured by former researches. However, the longitudinal changes brought by surgical treatment are not clear. In this research, 18 subjects who suffered from bilateral carpal tunnel syndrome were evaluated using t...

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Main Authors: Hao Ma, Yechen Lu, Xuyun Hua, Yundong Shen, Mouxiong Zheng, Wendong Xu
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2017/5101925
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spelling doaj-d7939c14dcf649b88476952df3ce9d6b2020-11-24T23:46:56ZengHindawi LimitedNeural Plasticity2090-59041687-54432017-01-01201710.1155/2017/51019255101925A Longitudinal fMRI Research on Neural Plasticity and Sensory Outcome of Carpal Tunnel SyndromeHao Ma0Yechen Lu1Xuyun Hua2Yundong Shen3Mouxiong Zheng4Wendong Xu5Department of Hand Surgery, Huashan Hospital, Fudan University, 12 Wulumuqi Middle Road, Shanghai 200040, ChinaDepartment of Hand Surgery, Huashan Hospital, Fudan University, 12 Wulumuqi Middle Road, Shanghai 200040, ChinaDepartment of Hand Surgery, Huashan Hospital, Fudan University, 12 Wulumuqi Middle Road, Shanghai 200040, ChinaDepartment of Hand Surgery, Huashan Hospital, Fudan University, 12 Wulumuqi Middle Road, Shanghai 200040, ChinaDepartment of Hand Surgery, Huashan Hospital, Fudan University, 12 Wulumuqi Middle Road, Shanghai 200040, ChinaDepartment of Hand Surgery, Huashan Hospital, Fudan University, 12 Wulumuqi Middle Road, Shanghai 200040, ChinaPeripheral nerve compression is reported to induce cortical plasticity, which was well pictured by former researches. However, the longitudinal changes brought by surgical treatment are not clear. In this research, 18 subjects who suffered from bilateral carpal tunnel syndrome were evaluated using task-dependent fMRI and electromyography assessment before and after surgery. The third digit was tactually simulated by von Frey filaments. The results demonstrated that the pattern of activation was similar but a decreased extent of activation in the postcentral gyrus, inferior frontal lobe, superior frontal lobe, and parahippocampal gyrus after surgery was found. The correlation analysis showed a significant correlation between the decreased number of activated voxels and the improvement of EMG performance. This result implied a potential connection between fMRI measurement and clinical improvement.http://dx.doi.org/10.1155/2017/5101925
collection DOAJ
language English
format Article
sources DOAJ
author Hao Ma
Yechen Lu
Xuyun Hua
Yundong Shen
Mouxiong Zheng
Wendong Xu
spellingShingle Hao Ma
Yechen Lu
Xuyun Hua
Yundong Shen
Mouxiong Zheng
Wendong Xu
A Longitudinal fMRI Research on Neural Plasticity and Sensory Outcome of Carpal Tunnel Syndrome
Neural Plasticity
author_facet Hao Ma
Yechen Lu
Xuyun Hua
Yundong Shen
Mouxiong Zheng
Wendong Xu
author_sort Hao Ma
title A Longitudinal fMRI Research on Neural Plasticity and Sensory Outcome of Carpal Tunnel Syndrome
title_short A Longitudinal fMRI Research on Neural Plasticity and Sensory Outcome of Carpal Tunnel Syndrome
title_full A Longitudinal fMRI Research on Neural Plasticity and Sensory Outcome of Carpal Tunnel Syndrome
title_fullStr A Longitudinal fMRI Research on Neural Plasticity and Sensory Outcome of Carpal Tunnel Syndrome
title_full_unstemmed A Longitudinal fMRI Research on Neural Plasticity and Sensory Outcome of Carpal Tunnel Syndrome
title_sort longitudinal fmri research on neural plasticity and sensory outcome of carpal tunnel syndrome
publisher Hindawi Limited
series Neural Plasticity
issn 2090-5904
1687-5443
publishDate 2017-01-01
description Peripheral nerve compression is reported to induce cortical plasticity, which was well pictured by former researches. However, the longitudinal changes brought by surgical treatment are not clear. In this research, 18 subjects who suffered from bilateral carpal tunnel syndrome were evaluated using task-dependent fMRI and electromyography assessment before and after surgery. The third digit was tactually simulated by von Frey filaments. The results demonstrated that the pattern of activation was similar but a decreased extent of activation in the postcentral gyrus, inferior frontal lobe, superior frontal lobe, and parahippocampal gyrus after surgery was found. The correlation analysis showed a significant correlation between the decreased number of activated voxels and the improvement of EMG performance. This result implied a potential connection between fMRI measurement and clinical improvement.
url http://dx.doi.org/10.1155/2017/5101925
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