Myeloid Sarcoma in a One-Month-Old Infant
Myeloid sarcoma, which sometimes accompanies recurrent systemic leukemia, is a rare manifestation of congenital leukemia. We describe the case of a 1-month-old Japanese girl with myeloid sarcoma, who did not fulfill the criteria of systemic leukemia. The physical examination revealed a bruise-like p...
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2011-09-01
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doaj-d799b24960f344e59668a26d109dd6e62020-11-24T22:14:33ZengKarger PublishersCase Reports in Dermatology1662-65672011-09-013321922210.1159/000333206333206Myeloid Sarcoma in a One-Month-Old InfantChihiro WakusawaTaku FujimuraAkira HashimotoSetsuya AibaMyeloid sarcoma, which sometimes accompanies recurrent systemic leukemia, is a rare manifestation of congenital leukemia. We describe the case of a 1-month-old Japanese girl with myeloid sarcoma, who did not fulfill the criteria of systemic leukemia. The physical examination revealed a bruise-like plaque on the right side of her chest. Histopathologically, there were CD4+ CD56– CD68+ atypical large lymphocytes densely infiltrating the upper dermis and the subcutaneous tissue. Biopsy specimens from bone marrow contained only 3.4% of blast cells, showing an abnormality of the mixed-lineage leukemia gene. The skin lesions disappeared 10 days after chemotherapy, and there was no recurrence for one and a half years.http://www.karger.com/Article/FullText/333206Myeloid sarcomaCD4Hematopoietic neoplasm |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Chihiro Wakusawa Taku Fujimura Akira Hashimoto Setsuya Aiba |
spellingShingle |
Chihiro Wakusawa Taku Fujimura Akira Hashimoto Setsuya Aiba Myeloid Sarcoma in a One-Month-Old Infant Case Reports in Dermatology Myeloid sarcoma CD4 Hematopoietic neoplasm |
author_facet |
Chihiro Wakusawa Taku Fujimura Akira Hashimoto Setsuya Aiba |
author_sort |
Chihiro Wakusawa |
title |
Myeloid Sarcoma in a One-Month-Old Infant |
title_short |
Myeloid Sarcoma in a One-Month-Old Infant |
title_full |
Myeloid Sarcoma in a One-Month-Old Infant |
title_fullStr |
Myeloid Sarcoma in a One-Month-Old Infant |
title_full_unstemmed |
Myeloid Sarcoma in a One-Month-Old Infant |
title_sort |
myeloid sarcoma in a one-month-old infant |
publisher |
Karger Publishers |
series |
Case Reports in Dermatology |
issn |
1662-6567 |
publishDate |
2011-09-01 |
description |
Myeloid sarcoma, which sometimes accompanies recurrent systemic leukemia, is a rare manifestation of congenital leukemia. We describe the case of a 1-month-old Japanese girl with myeloid sarcoma, who did not fulfill the criteria of systemic leukemia. The physical examination revealed a bruise-like plaque on the right side of her chest. Histopathologically, there were CD4+ CD56– CD68+ atypical large lymphocytes densely infiltrating the upper dermis and the subcutaneous tissue. Biopsy specimens from bone marrow contained only 3.4% of blast cells, showing an abnormality of the mixed-lineage leukemia gene. The skin lesions disappeared 10 days after chemotherapy, and there was no recurrence for one and a half years. |
topic |
Myeloid sarcoma CD4 Hematopoietic neoplasm |
url |
http://www.karger.com/Article/FullText/333206 |
work_keys_str_mv |
AT chihirowakusawa myeloidsarcomainaonemontholdinfant AT takufujimura myeloidsarcomainaonemontholdinfant AT akirahashimoto myeloidsarcomainaonemontholdinfant AT setsuyaaiba myeloidsarcomainaonemontholdinfant |
_version_ |
1725798362046791680 |