Clinical study on transsphenoidal approach under endoscope for repairing cerebrospinal fluid rhinorrhea after pituitary adenoma resection

• Main Authors: Huan-xin YU, Hai-yan LI, Gang LIU
• Format: Article
• Language: English
• Published: Tianjin Huanhu Hospital 2017-06-01
• Series: Chinese Journal of Contemporary Neurology and Neurosurgery
• Subjects: Pituitary neoplasms; Adenoma; Sphenoid sinus; Cerebrospinal fluid rhinorrhea; Endoscopy
• Online Access: http://www.cjcnn.org/index.php/cjcnn/article/view/1620

<p><strong>Objective </strong>To summarize the experience of endoscopic surgery by transsphenoidal approach for repairing cerebrospinal fluid (CSF) rhinorrhea after pituitary adenoma resection.  <strong>Methods </strong>Clinical data, operation skills and follow-up data of 16 cases of persistent CSF rhinorrhea after pituitary adenoma resection from March 2009 to July 2014 were retrospectively analyzed.  <strong>Results</strong> All patients were repaired by endoscopic transsphenoidal approach, 13 cases (13/16) were successful by one reparative surgery, 2 cases (2/16) were successful by the second repairment, and one case (1/16) was failed by several endoscopic surgeries, but was successfully repaired by craniotomy. One case presented intracranial infection after surgery, and recovered after taking ceftriaxone. After postoperative follow-up for 6 months to 2 years (average 12 months), no tumor recurrence or CSF rhinorrhea recurrence occurred.  <strong>Conclusions </strong>Endoscopic transsphenoidal approach for repairing CSF rhinorrhea after pituitary adenoma resection was safe and effective. It can be widely used in clinic.</p><p> </p><p><strong>DOI: </strong>10.3969/j.issn.1672-6731.2017.06.012</p>