Molecular detection of leptospirosis and melioidosis co-infection: A case report
Leptospirosis and melioidosis are important tropical infections caused by Leptospira and Burkholdheria pseudomallei, respectively. As both infections share similar clinical manifestations yet require different managements, complementary laboratory tests are crucial for the diagnosis. We describe a c...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2017-11-01
|
Series: | Journal of Infection and Public Health |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1876034117300874 |
id |
doaj-d7afd4091cfc4b65be715f6682075b0e |
---|---|
record_format |
Article |
spelling |
doaj-d7afd4091cfc4b65be715f6682075b0e2020-11-24T21:22:19ZengElsevierJournal of Infection and Public Health1876-03412017-11-01106894896Molecular detection of leptospirosis and melioidosis co-infection: A case reportMohammad R. Mohd Ali0Amira W. Mohamad Safiee1Padmaloseni Thangarajah2Mohd H. Fauzi3Alwi Muhd Besari4Nabilah Ismail5Chan Yean Yean6Department of Medical Microbiology & Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia; Secretariat National Institutes of Health (NIH), Ministry of Health Malaysia, c/o Institut Pengurusan Kesihatan, Jalan Rumah Sakit Bangsar, 59000 Kuala Lumpur, MalaysiaDepartment of Medical Microbiology & Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, MalaysiaDepartment of Medical Microbiology & Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, MalaysiaDepartment of Emergency Medicine, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, MalaysiaDepartment of Medicine, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, MalaysiaDepartment of Medical Microbiology & Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, MalaysiaDepartment of Medical Microbiology & Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia; Corresponding author.Leptospirosis and melioidosis are important tropical infections caused by Leptospira and Burkholdheria pseudomallei, respectively. As both infections share similar clinical manifestations yet require different managements, complementary laboratory tests are crucial for the diagnosis. We describe a case of Leptospira and B. pseudomallei co-infection in a diabetic 40-year-old woman with history of visit to a freshwater camping site in northern Malaysia. To our knowledge, this is the first case of such double-infection, simultaneously demonstrated by molecular approach. This case highlights the possibility of leptospirosis and melioidosis co-infections and their underlying challenges in the rapid and accurate detection of the etiologic microorganism. Keywords: Leptospirosis, Melioidosis, Co-infection, PCR, Febrilehttp://www.sciencedirect.com/science/article/pii/S1876034117300874 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mohammad R. Mohd Ali Amira W. Mohamad Safiee Padmaloseni Thangarajah Mohd H. Fauzi Alwi Muhd Besari Nabilah Ismail Chan Yean Yean |
spellingShingle |
Mohammad R. Mohd Ali Amira W. Mohamad Safiee Padmaloseni Thangarajah Mohd H. Fauzi Alwi Muhd Besari Nabilah Ismail Chan Yean Yean Molecular detection of leptospirosis and melioidosis co-infection: A case report Journal of Infection and Public Health |
author_facet |
Mohammad R. Mohd Ali Amira W. Mohamad Safiee Padmaloseni Thangarajah Mohd H. Fauzi Alwi Muhd Besari Nabilah Ismail Chan Yean Yean |
author_sort |
Mohammad R. Mohd Ali |
title |
Molecular detection of leptospirosis and melioidosis co-infection: A case report |
title_short |
Molecular detection of leptospirosis and melioidosis co-infection: A case report |
title_full |
Molecular detection of leptospirosis and melioidosis co-infection: A case report |
title_fullStr |
Molecular detection of leptospirosis and melioidosis co-infection: A case report |
title_full_unstemmed |
Molecular detection of leptospirosis and melioidosis co-infection: A case report |
title_sort |
molecular detection of leptospirosis and melioidosis co-infection: a case report |
publisher |
Elsevier |
series |
Journal of Infection and Public Health |
issn |
1876-0341 |
publishDate |
2017-11-01 |
description |
Leptospirosis and melioidosis are important tropical infections caused by Leptospira and Burkholdheria pseudomallei, respectively. As both infections share similar clinical manifestations yet require different managements, complementary laboratory tests are crucial for the diagnosis. We describe a case of Leptospira and B. pseudomallei co-infection in a diabetic 40-year-old woman with history of visit to a freshwater camping site in northern Malaysia. To our knowledge, this is the first case of such double-infection, simultaneously demonstrated by molecular approach. This case highlights the possibility of leptospirosis and melioidosis co-infections and their underlying challenges in the rapid and accurate detection of the etiologic microorganism. Keywords: Leptospirosis, Melioidosis, Co-infection, PCR, Febrile |
url |
http://www.sciencedirect.com/science/article/pii/S1876034117300874 |
work_keys_str_mv |
AT mohammadrmohdali moleculardetectionofleptospirosisandmelioidosiscoinfectionacasereport AT amirawmohamadsafiee moleculardetectionofleptospirosisandmelioidosiscoinfectionacasereport AT padmalosenithangarajah moleculardetectionofleptospirosisandmelioidosiscoinfectionacasereport AT mohdhfauzi moleculardetectionofleptospirosisandmelioidosiscoinfectionacasereport AT alwimuhdbesari moleculardetectionofleptospirosisandmelioidosiscoinfectionacasereport AT nabilahismail moleculardetectionofleptospirosisandmelioidosiscoinfectionacasereport AT chanyeanyean moleculardetectionofleptospirosisandmelioidosiscoinfectionacasereport |
_version_ |
1725996356620779520 |