Necrolytic migratory ulceration
Endocrine tumors of the gastroenteropancreatic system associated with specific skin manifestations are rare. We report a 53-year-old female who presented with migratory annular and arcuate ulcers on her limbs. Histopathology was similar to necrolytic erythema family which includes necrolytic migrato...
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Wolters Kluwer Medknow Publications
2013-01-01
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Online Access: | http://www.idoj.in/article.asp?issn=2229-5178;year=2013;volume=4;issue=3;spage=205;epage=207;aulast=Pakran |
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doaj-d7b324723856479abc83edfd4e0142452020-11-24T22:49:23ZengWolters Kluwer Medknow PublicationsIndian Dermatology Online Journal2229-51782013-01-014320520710.4103/2229-5178.115518Necrolytic migratory ulcerationJaheersha PakranNajeeba RiyazEndocrine tumors of the gastroenteropancreatic system associated with specific skin manifestations are rare. We report a 53-year-old female who presented with migratory annular and arcuate ulcers on her limbs. Histopathology was similar to necrolytic erythema family which includes necrolytic migratory erythema (NME). Though initial CT scans were normal, follow up scans revealed multiple mass lesions in the tail of pancreas. Her skin lesions responded to oral zinc sulphate and monthly injections of octreotide. Prior to planned FNAC from the mass lesion, patient developed altered sensorium and succumbed to the disease. This case report seems to differ from NME clinically, due to unique finding of deep migrating ulcers which heal with scarring. ′Necrolytic migratory ulceration′ thus appears to be a new paraneoplastic manifestation, secondary to pancreatic malignancy.http://www.idoj.in/article.asp?issn=2229-5178;year=2013;volume=4;issue=3;spage=205;epage=207;aulast=PakranMigratory ulcersnecrolytic erythemanecrolytic migratory erythemapancreatic tumor |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jaheersha Pakran Najeeba Riyaz |
spellingShingle |
Jaheersha Pakran Najeeba Riyaz Necrolytic migratory ulceration Indian Dermatology Online Journal Migratory ulcers necrolytic erythema necrolytic migratory erythema pancreatic tumor |
author_facet |
Jaheersha Pakran Najeeba Riyaz |
author_sort |
Jaheersha Pakran |
title |
Necrolytic migratory ulceration |
title_short |
Necrolytic migratory ulceration |
title_full |
Necrolytic migratory ulceration |
title_fullStr |
Necrolytic migratory ulceration |
title_full_unstemmed |
Necrolytic migratory ulceration |
title_sort |
necrolytic migratory ulceration |
publisher |
Wolters Kluwer Medknow Publications |
series |
Indian Dermatology Online Journal |
issn |
2229-5178 |
publishDate |
2013-01-01 |
description |
Endocrine tumors of the gastroenteropancreatic system associated with specific skin manifestations are rare. We report a 53-year-old female who presented with migratory annular and arcuate ulcers on her limbs. Histopathology was similar to necrolytic erythema family which includes necrolytic migratory erythema (NME). Though initial CT scans were normal, follow up scans revealed multiple mass lesions in the tail of pancreas. Her skin lesions responded to oral zinc sulphate and monthly injections of octreotide. Prior to planned FNAC from the mass lesion, patient developed altered sensorium and succumbed to the disease. This case report seems to differ from NME clinically, due to unique finding of deep migrating ulcers which heal with scarring. ′Necrolytic migratory ulceration′ thus appears to be a new paraneoplastic manifestation, secondary to pancreatic malignancy. |
topic |
Migratory ulcers necrolytic erythema necrolytic migratory erythema pancreatic tumor |
url |
http://www.idoj.in/article.asp?issn=2229-5178;year=2013;volume=4;issue=3;spage=205;epage=207;aulast=Pakran |
work_keys_str_mv |
AT jaheershapakran necrolyticmigratoryulceration AT najeebariyaz necrolyticmigratoryulceration |
_version_ |
1725676072682389504 |