Gene Editing of HIV-1 Co-receptors to Prevent and/or Cure Virus Infection

Gene Editing of HIV-1 Co-receptors to Prevent and/or Cure Virus Infection

Antiretroviral therapy has prolonged the lives of people living with human immunodeficiency virus type 1 (HIV-1), transforming the disease into one that can be controlled with lifelong therapy. The search for an HIV-1 vaccine has plagued researchers for more than three decades with little to no succ...

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Bibliographic Details
Main Authors: Alexander G. Allen, Cheng-Han Chung, Andrew Atkins, Will Dampier, Kamel Khalili, Michael R. Nonnemacher, Brian Wigdahl
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Microbiology
Subjects:
CRISPR/Cas9
HIV-1
CXCR4
CCR5
CD4
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02940/full

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