Upregulation of cannabinoid receptor type 2, but not TSPO, in senescence-accelerated neuroinflammation in mice: a positron emission tomography study
Abstract Background Microglial cells are activated in response to changes in brain homeostasis during aging, dementia, and stroke. Type 2 endocannabinoid receptors (CB2) and translocator protein 18 kD (TSPO) are considered to reflect distinct aspects of microglia-related neuroinflammatory responses...
Main Authors: | Satoru Yamagishi, Yurika Iga, Masato Nakamura, Chika Takizawa, Dai Fukumoto, Takeharu Kakiuchi, Shingo Nishiyama, Hiroyuki Ohba, Hideo Tsukada, Kohji Sato, Yasuomi Ouchi |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2019-11-01
|
Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12974-019-1604-3 |
Similar Items
Emerging Role of (Endo)Cannabinoids in Migraine
by: Pinja Leimuranta, et al.
Published: (2018-04-01)
by: Pinja Leimuranta, et al.
Published: (2018-04-01)
Similar Items
-
In vivo TSPO and cannabinoid receptor type 2 availability early in post-stroke neuroinflammation in rats: a positron emission tomography study
by: Teruyo Hosoya, et al.
Published: (2017-03-01) -
Positive Allosteric Modulation of CB1 and CB2 Cannabinoid Receptors Enhances the Neuroprotective Activity of a Dual CB1R/CB2R Orthosteric Agonist
by: Beatrice Polini, et al.
Published: (2020-12-01) -
Cannabinoids attenuate the effects of aging upon neuroinflammation and neurogenesis
by: Yannick Marchalant, et al.
Published: (2009-05-01) -
Recent developments on PET radiotracers for TSPO and their applications in neuroimaging
by: Lingling Zhang, et al.
Published: (2021-02-01) -
The use of cannabinoids in epilepsy as an example: medical, social, and legal aspects
by: R. G. Akzhigitov, et al.
Published: (2020-08-01)