Treatment options for atypical optic neuritis
Context: Optic neuritis (ON) is defined as inflammation of the optic nerve and can have various etiologies. The most common presentation in the US is demyelinating, or "typical" ON, usually associated with multiple sclerosis. This is in contrast to "atypical" causes of ON, which...
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doaj-d7fbb62f912a4f5fb798652dbe0f8bce2020-11-24T20:56:57ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892014-01-01621098298410.4103/0301-4738.145986Treatment options for atypical optic neuritisAmina MalikMaryam AhmedKarl GolnikContext: Optic neuritis (ON) is defined as inflammation of the optic nerve and can have various etiologies. The most common presentation in the US is demyelinating, or "typical" ON, usually associated with multiple sclerosis. This is in contrast to "atypical" causes of ON, which differ in their clinical presentation, management, and prognosis. These atypical cases are characterized by lack of eye pain, exudates, and hemorrhages on exam, very severe, bilateral or progressive visual loss, or with failure to recover vision. Aims: The aim was to describe the clinical presentations of atypical ON and their treatments. Settings and Design: Review article. Materials and Methods: Literature review. Results: Types of atypical ON identified include neuromyelitis optica, autoimmune optic neuropathy, chronic relapsing inflammatory optic neuropathy, idiopathic recurrent neuroretinitis, and optic neuropathy associated with systemic diseases. Atypical ON usually requires corticosteroid treatment and often will require aggressive immunosuppression. Conclusions: Unlike demyelinating ON, atypical ON requires treatment to preserve vision.http://www.ijo.in/article.asp?issn=0301-4738;year=2014;volume=62;issue=10;spage=982;epage=984;aulast=MalikAtypical optic neuritisautoimmunitymultiple sclerosisneuromyelitis opticaneuroretinitisoptic neuritisoptic neuropathy |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Amina Malik Maryam Ahmed Karl Golnik |
spellingShingle |
Amina Malik Maryam Ahmed Karl Golnik Treatment options for atypical optic neuritis Indian Journal of Ophthalmology Atypical optic neuritis autoimmunity multiple sclerosis neuromyelitis optica neuroretinitis optic neuritis optic neuropathy |
author_facet |
Amina Malik Maryam Ahmed Karl Golnik |
author_sort |
Amina Malik |
title |
Treatment options for atypical optic neuritis |
title_short |
Treatment options for atypical optic neuritis |
title_full |
Treatment options for atypical optic neuritis |
title_fullStr |
Treatment options for atypical optic neuritis |
title_full_unstemmed |
Treatment options for atypical optic neuritis |
title_sort |
treatment options for atypical optic neuritis |
publisher |
Wolters Kluwer Medknow Publications |
series |
Indian Journal of Ophthalmology |
issn |
0301-4738 1998-3689 |
publishDate |
2014-01-01 |
description |
Context: Optic neuritis (ON) is defined as inflammation of the optic nerve and can have various etiologies. The most common presentation in the US is demyelinating, or "typical" ON, usually associated with multiple sclerosis. This is in contrast to "atypical" causes of ON, which differ in their clinical presentation, management, and prognosis. These atypical cases are characterized by lack of eye pain, exudates, and hemorrhages on exam, very severe, bilateral or progressive visual loss, or with failure to recover vision. Aims: The aim was to describe the clinical presentations of atypical ON and their treatments. Settings and Design: Review article. Materials and Methods: Literature review. Results: Types of atypical ON identified include neuromyelitis optica, autoimmune optic neuropathy, chronic relapsing inflammatory optic neuropathy, idiopathic recurrent neuroretinitis, and optic neuropathy associated with systemic diseases. Atypical ON usually requires corticosteroid treatment and often will require aggressive immunosuppression. Conclusions: Unlike demyelinating ON, atypical ON requires treatment to preserve vision. |
topic |
Atypical optic neuritis autoimmunity multiple sclerosis neuromyelitis optica neuroretinitis optic neuritis optic neuropathy |
url |
http://www.ijo.in/article.asp?issn=0301-4738;year=2014;volume=62;issue=10;spage=982;epage=984;aulast=Malik |
work_keys_str_mv |
AT aminamalik treatmentoptionsforatypicalopticneuritis AT maryamahmed treatmentoptionsforatypicalopticneuritis AT karlgolnik treatmentoptionsforatypicalopticneuritis |
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