Nucleic Acid Based Fluorinated Derivatives: New Tools for Biomedical Applications

Nucleic Acid Based Fluorinated Derivatives: New Tools for Biomedical Applications

Nucleic acid-based fluorinated derivatives, e.g., nucleosides or oligonucleotides connected to highly fluorinated chains or labeled with one or more fluorine atoms, have been investigated recently due to their high potential for biomedical applications. This review deals with recent works on nucleos...

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Bibliographic Details
Main Authors: Christel Dolain, Amit Patwa, Guilhem Godeau, Philippe Barthélémy
Format: Article
Language:English
Published: MDPI AG 2012-03-01
Series:Applied Sciences
Subjects:
fluorocarbon
amphiphile
lipids
nucleoside
oligonucleotides
Online Access:http://www.mdpi.com/2076-3417/2/2/245
Description
Summary:Nucleic acid-based fluorinated derivatives, e.g., nucleosides or oligonucleotides connected to highly fluorinated chains or labeled with one or more fluorine atoms, have been investigated recently due to their high potential for biomedical applications. This review deals with recent works on nucleoside and oligonucleotide fluorocarbon amphiphiles as well as with properties and applications of fluorine-labeled oligonucleotide analogues.
ISSN:2076-3417

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