Identification of tumor suppressors and oncogenes from genomic and epigenetic features in ovarian cancer.

The identification of genetic and epigenetic alterations from primary tumor cells has become a common method to identify genes critical to the development and progression of cancer. We seek to identify those genetic and epigenetic aberrations that have the most impact on gene function within the tum...

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Bibliographic Details
Main Authors: Kazimierz O Wrzeszczynski, Vinay Varadan, James Byrnes, Elena Lum, Sitharthan Kamalakaran, Douglas A Levine, Nevenka Dimitrova, Michael Q Zhang, Robert Lucito
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3234280?pdf=render

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