Construction of Escherichia coli Whole-Cell Biosensors for Statin Efficacy and Production Test
Statins are widely used cholesterol-lowering drugs. Their potential application in anti-cancer treatment is also under investigation. The individual variance in statin response has been observed, which may be caused by the variation in human HMG-CoA reductase (hHMGR)—the inhibition target of statin...
Main Authors: | Huanjie Li, Qingda Wang, Rui Zhao, Yunshan Wang, Luying Xun, Huaiwei Liu |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-05-01
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Series: | Frontiers in Cell and Developmental Biology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fcell.2020.00404/full |
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