The lncRNA MEG3 downregulation leads to osteoarthritis progression via miR-16/SMAD7 axis
Abstract Background Osteoarthritis (OA) is a chronic joint disease and there is no a definitive cure at present. Long non-coding RNAs (lncRNAs) have been confirmed to play important roles in the development of OA. However, the underlying mechanism of lncRNA maternally expressed gene 3 (MEG3) in OA h...
Main Authors: | Jin Xu, Yaozeng Xu |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2017-12-01
|
Series: | Cell & Bioscience |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13578-017-0195-x |
Similar Items
-
LncRNA HOTTIP leads to osteoarthritis progression via regulating miR-663a/ Fyn-related kinase axis
by: Xianwei He, et al.
Published: (2021-01-01) -
The emerging role of lncRNAs in chondrocytes from osteoarthritis patients
by: Jiajie Tu, et al.
Published: (2020-11-01) -
Clinical Value of lncRNA MEG3 in High-Grade Serous Ovarian Cancer
by: Marianna Buttarelli, et al.
Published: (2020-04-01) -
LncRNA ANRIL/miR-7-5p/TCF4 axis contributes to the progression of T cell acute lymphoblastic leukemia
by: Gang Li, et al.
Published: (2020-07-01) -
The Impact of Single Nucleotide Polymorphism in the Long Non-coding MEG3 Gene on MicroRNA-182 and MicroRNA-29 Expression Levels in the Development of Breast Cancer in Egyptian Women
by: Olfat Shaker, et al.
Published: (2021-08-01)