Rapid Transmission of a Hyper-Virulent Meningococcal Clone Due to High Effective Contact Numbers and Super Spreaders

Rapid Transmission of a Hyper-Virulent Meningococcal Clone Due to High Effective Contact Numbers and Super Spreaders

Rapid transmission, a critical contributory factor in outbreaks of invasive meningococcal disease, requires naïve populations of sufficient size and intermingling. We examined genomic variability and transmission dynamics in a student population subject to an 11-fold increase in carriage of a hyperv...

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Bibliographic Details
Main Authors: Jonathan C. Holmes, Luke R. Green, Neil J. Oldfield, David P.J. Turner, Christopher D. Bayliss
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Genetics
Subjects:
Neisseria meningitidis
meningococcus
meningitis
asymptomatic carriage
transmission
mathematical model
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.579411/full

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