A Virulence Associated Siderophore Importer Reduces Antimicrobial Susceptibility of Klebsiella pneumoniae

A Virulence Associated Siderophore Importer Reduces Antimicrobial Susceptibility of Klebsiella pneumoniae

The accessory genomes of many pathogenic bacteria include ABC transporters that scavenge metal by siderophore uptake and ABC transporters that contribute to antimicrobial resistance by multidrug efflux. There are mechanistic and recently recognized structural similarities between siderophore importe...

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Bibliographic Details
Main Authors: Robeena Farzand, Kumar Rajakumar, Michael R. Barer, Primrose P. E. Freestone, Galina V. Mukamolova, Marco R. Oggioni, Helen M. O’Hare
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Microbiology
Subjects:
Klebsiella pneumoniae
yersiniabactin
ABC transporter
antimicrobial efflux
siderophore
mobile genetic element
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.607512/full

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