Serum bilirubin and ischaemic stroke: a review of literature

Serum bilirubin and ischaemic stroke: a review of literature

Bilirubin, a product of heme metabolism, is the most potent endogenous antioxidant which increases in many oxidative stress conditions such as stroke. It has been widely known to exert neuroprotective effect on stroke through mechanisms involved in development, therefore, it can influence the occurr...

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Main Authors: Xiao Wang, Danhong Wu, Ping Zhong
Format: Article
Language:English
Published: BMJ Publishing Group 2020-06-01
Series:Stroke and Vascular Neurology
Online Access:https://svn.bmj.com/content/5/2/198.full
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spelling doaj-d86275d2430547aba5c266b567d23fd52020-11-25T03:21:56ZengBMJ Publishing GroupStroke and Vascular Neurology2059-86962020-06-015210.1136/svn-2019-000289Serum bilirubin and ischaemic stroke: a review of literatureXiao Wang0Danhong Wu1Ping Zhong21 Department of Neurology, Shanghai Traditional Chinese and Western Medicine Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China2 Department of Neurology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, China3 Department of Neurology, Shanghai Traditional Chinese and Western Medicine Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaBilirubin, a product of heme metabolism, is the most potent endogenous antioxidant which increases in many oxidative stress conditions such as stroke. It has been widely known to exert neuroprotective effect on stroke through mechanisms involved in development, therefore, it can influence the occurrence and prognosis of ischaemic stroke (IS). In this review, studies were identified by a comprehensive search of Pubmed, Embase, the Cochrane Library (Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Methodology Register) and Web of Science to examine the correlation between serum bilirubin levels and risks of developing IS as well as IS outcomes. Additional studies were identified by reviewing references and contacting authors.https://svn.bmj.com/content/5/2/198.full
collection DOAJ
language English
format Article
sources DOAJ
author Xiao Wang
Danhong Wu
Ping Zhong
spellingShingle Xiao Wang
Danhong Wu
Ping Zhong
Serum bilirubin and ischaemic stroke: a review of literature
Stroke and Vascular Neurology
author_facet Xiao Wang
Danhong Wu
Ping Zhong
author_sort Xiao Wang
title Serum bilirubin and ischaemic stroke: a review of literature
title_short Serum bilirubin and ischaemic stroke: a review of literature
title_full Serum bilirubin and ischaemic stroke: a review of literature
title_fullStr Serum bilirubin and ischaemic stroke: a review of literature
title_full_unstemmed Serum bilirubin and ischaemic stroke: a review of literature
title_sort serum bilirubin and ischaemic stroke: a review of literature
publisher BMJ Publishing Group
series Stroke and Vascular Neurology
issn 2059-8696
publishDate 2020-06-01
description Bilirubin, a product of heme metabolism, is the most potent endogenous antioxidant which increases in many oxidative stress conditions such as stroke. It has been widely known to exert neuroprotective effect on stroke through mechanisms involved in development, therefore, it can influence the occurrence and prognosis of ischaemic stroke (IS). In this review, studies were identified by a comprehensive search of Pubmed, Embase, the Cochrane Library (Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Methodology Register) and Web of Science to examine the correlation between serum bilirubin levels and risks of developing IS as well as IS outcomes. Additional studies were identified by reviewing references and contacting authors.
url https://svn.bmj.com/content/5/2/198.full
work_keys_str_mv AT xiaowang serumbilirubinandischaemicstrokeareviewofliterature
AT danhongwu serumbilirubinandischaemicstrokeareviewofliterature
AT pingzhong serumbilirubinandischaemicstrokeareviewofliterature
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