Learning and Memory Recoveries in a Young Girl Treated with Growth Hormone and Neurorehabilitation
Background—To describe the results obtained after treating a non growth hormone-deficient 10-year-old girl who suffered asphyxia during delivery, resulting in important cognitive deficits, with growth hormone (GH) and neurorehabilitation. Methods—GH was administered (mg/day) at doses of 0.5 over thr...
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doaj-d86e056fb6de4b84b86d5858c77a0d4c2020-11-24T23:25:27ZengMDPI AGJournal of Clinical Medicine2077-03832016-01-01521410.3390/jcm5020014jcm5020014Learning and Memory Recoveries in a Young Girl Treated with Growth Hormone and NeurorehabilitationJesús Devesa0Hortensia Lema1Eva Zas2Borja Munín3Pilar Taboada4Pablo Devesa5Medical Centre Foltra, Travesía de Montouto 24, Teo 15886, SpainMedical Centre Foltra, Travesía de Montouto 24, Teo 15886, SpainMedical Centre Foltra, Travesía de Montouto 24, Teo 15886, SpainMedical Centre Foltra, Travesía de Montouto 24, Teo 15886, SpainMedical Centre Foltra, Travesía de Montouto 24, Teo 15886, SpainMedical Centre Foltra, Travesía de Montouto 24, Teo 15886, SpainBackground—To describe the results obtained after treating a non growth hormone-deficient 10-year-old girl who suffered asphyxia during delivery, resulting in important cognitive deficits, with growth hormone (GH) and neurorehabilitation. Methods—GH was administered (mg/day) at doses of 0.5 over three months followed by 0.9, every two weeks over three months, and then alternating 1.2 three days/week and 0.3 two days/week. Neurorehabilitation consisted of daily sessions of neurostimulation, speech therapy, occupational therapy and auditive stimulation. Treatment lasted nine months. Results—Scores obtained in all the areas treated showed that, at discharge, the patient clearly increased her cognitive abilities, memory and language competence index; her intelligence quotient score increased from 51 to 80, and the index of functional independence measure reached a value of 120 over 126 (maximal value). Conclusions—This case suggests that GH administration may play a role in improving cognitive deficits during neurorehabilitation in children with brain damage suffered during delivery. This agrees with the known effects of GH on cognition.http://www.mdpi.com/2077-0383/5/2/14growth hormoneneurorehabilitationbrain plasticitycognitive functionsmemorynatal asphyxia |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jesús Devesa Hortensia Lema Eva Zas Borja Munín Pilar Taboada Pablo Devesa |
spellingShingle |
Jesús Devesa Hortensia Lema Eva Zas Borja Munín Pilar Taboada Pablo Devesa Learning and Memory Recoveries in a Young Girl Treated with Growth Hormone and Neurorehabilitation Journal of Clinical Medicine growth hormone neurorehabilitation brain plasticity cognitive functions memory natal asphyxia |
author_facet |
Jesús Devesa Hortensia Lema Eva Zas Borja Munín Pilar Taboada Pablo Devesa |
author_sort |
Jesús Devesa |
title |
Learning and Memory Recoveries in a Young Girl Treated with Growth Hormone and Neurorehabilitation |
title_short |
Learning and Memory Recoveries in a Young Girl Treated with Growth Hormone and Neurorehabilitation |
title_full |
Learning and Memory Recoveries in a Young Girl Treated with Growth Hormone and Neurorehabilitation |
title_fullStr |
Learning and Memory Recoveries in a Young Girl Treated with Growth Hormone and Neurorehabilitation |
title_full_unstemmed |
Learning and Memory Recoveries in a Young Girl Treated with Growth Hormone and Neurorehabilitation |
title_sort |
learning and memory recoveries in a young girl treated with growth hormone and neurorehabilitation |
publisher |
MDPI AG |
series |
Journal of Clinical Medicine |
issn |
2077-0383 |
publishDate |
2016-01-01 |
description |
Background—To describe the results obtained after treating a non growth hormone-deficient 10-year-old girl who suffered asphyxia during delivery, resulting in important cognitive deficits, with growth hormone (GH) and neurorehabilitation. Methods—GH was administered (mg/day) at doses of 0.5 over three months followed by 0.9, every two weeks over three months, and then alternating 1.2 three days/week and 0.3 two days/week. Neurorehabilitation consisted of daily sessions of neurostimulation, speech therapy, occupational therapy and auditive stimulation. Treatment lasted nine months. Results—Scores obtained in all the areas treated showed that, at discharge, the patient clearly increased her cognitive abilities, memory and language competence index; her intelligence quotient score increased from 51 to 80, and the index of functional independence measure reached a value of 120 over 126 (maximal value). Conclusions—This case suggests that GH administration may play a role in improving cognitive deficits during neurorehabilitation in children with brain damage suffered during delivery. This agrees with the known effects of GH on cognition. |
topic |
growth hormone neurorehabilitation brain plasticity cognitive functions memory natal asphyxia |
url |
http://www.mdpi.com/2077-0383/5/2/14 |
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