In vivo cigarette smoke exposure decreases CCL20, SLPI, and BD-1 secretion by human primary nasal epithelial cells.

In vivo cigarette smoke exposure decreases CCL20, SLPI, and BD-1 secretion by human primary nasal epithelial cells.

AbstractSmokers and individuals exposed to second hand cigarette smoke (SHCS) have a higher risk of developing chronic sinus and bronchial infections. This suggests that cigarette smoke (CS) has adverse effects on immune defenses against pathogens. Epithelial cells are important in airway innate im...

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Bibliographic Details
Main Authors: James eJukosky, Benoit J. Gosselin, Leah eFoley, Tenzin eDechen, Steven N. Fiering, Mardi A. Crane-Godreau
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Psychiatry
Subjects:
antimicrobial peptides
innate immune response
CCL20
SLPI
Cigarette smoke exposure
Primary nasal epithelium
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpsyt.2015.00185/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fpsyt.2015.00185/full

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