Sterol-Response Pathways Mediate Alkaline Survival in Diverse Fungi

The work described here further elucidates how microorganisms sense and adapt to changes in their environment to establish infections in the human host. Specifically, we uncover a novel mechanism by which an opportunistic human fungal pathogen, Cryptococcus neoformans, responds to increases in extra...

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Bibliographic Details
Main Authors: Hannah E. Brown, Calla L. Telzrow, Joseph W. Saelens, Larissa Fernandes, J. Andrew Alspaugh
Format: Article
Language:English
Published: American Society for Microbiology 2020-06-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.00719-20