Metabolic modelling reveals the specialization of secondary replicons for niche adaptation in Sinorhizobium meliloti

The genome of some bacteria consists of two or more chromosomes or replicons. Here, diCenzo et al. integrate genome-scale metabolic modelling and growth data from a collection of mutants of the plant symbiont Sinorhizobium melilotito estimate the fitness contribution of each replicon in three enviro...

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Main Authors:	George C. diCenzo, Alice Checcucci, Marco Bazzicalupo, Alessio Mengoni, Carlo Viti, Lukasz Dziewit, Turlough M. Finan, Marco Galardini, Marco Fondi
Format:	Article
Language:	English
Published:	Nature Publishing Group 2016-07-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/ncomms12219

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spelling	doaj-d88cc4dd211a489280d7429037268cff2021-05-11T11:06:21ZengNature Publishing GroupNature Communications2041-17232016-07-017111010.1038/ncomms12219Metabolic modelling reveals the specialization of secondary replicons for niche adaptation in Sinorhizobium melilotiGeorge C. diCenzo0Alice Checcucci1Marco Bazzicalupo2Alessio Mengoni3Carlo Viti4Lukasz Dziewit5Turlough M. Finan6Marco Galardini7Marco Fondi8Department of Biology, McMaster UniversityDepartment of Biology, University of FlorenceDepartment of Biology, University of FlorenceDepartment of Biology, University of FlorenceDepartment of Agri-food Production and Environmental Sciences, University of FlorenceDepartment of Bacterial Genetics, Institute of Microbiology, Faculty of Biology, University of WarsawDepartment of Biology, McMaster UniversityEMBL-EBI, Wellcome Trust Genome CampusDepartment of Biology, University of FlorenceThe genome of some bacteria consists of two or more chromosomes or replicons. Here, diCenzo et al. integrate genome-scale metabolic modelling and growth data from a collection of mutants of the plant symbiont Sinorhizobium melilotito estimate the fitness contribution of each replicon in three environments.https://doi.org/10.1038/ncomms12219
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	George C. diCenzo Alice Checcucci Marco Bazzicalupo Alessio Mengoni Carlo Viti Lukasz Dziewit Turlough M. Finan Marco Galardini Marco Fondi
spellingShingle	George C. diCenzo Alice Checcucci Marco Bazzicalupo Alessio Mengoni Carlo Viti Lukasz Dziewit Turlough M. Finan Marco Galardini Marco Fondi Metabolic modelling reveals the specialization of secondary replicons for niche adaptation in Sinorhizobium meliloti Nature Communications
author_facet	George C. diCenzo Alice Checcucci Marco Bazzicalupo Alessio Mengoni Carlo Viti Lukasz Dziewit Turlough M. Finan Marco Galardini Marco Fondi
author_sort	George C. diCenzo
title	Metabolic modelling reveals the specialization of secondary replicons for niche adaptation in Sinorhizobium meliloti
title_short	Metabolic modelling reveals the specialization of secondary replicons for niche adaptation in Sinorhizobium meliloti
title_full	Metabolic modelling reveals the specialization of secondary replicons for niche adaptation in Sinorhizobium meliloti
title_fullStr	Metabolic modelling reveals the specialization of secondary replicons for niche adaptation in Sinorhizobium meliloti
title_full_unstemmed	Metabolic modelling reveals the specialization of secondary replicons for niche adaptation in Sinorhizobium meliloti
title_sort	metabolic modelling reveals the specialization of secondary replicons for niche adaptation in sinorhizobium meliloti
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2016-07-01
description	The genome of some bacteria consists of two or more chromosomes or replicons. Here, diCenzo et al. integrate genome-scale metabolic modelling and growth data from a collection of mutants of the plant symbiont Sinorhizobium melilotito estimate the fitness contribution of each replicon in three environments.
url	https://doi.org/10.1038/ncomms12219
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Metabolic modelling reveals the specialization of secondary replicons for niche adaptation in Sinorhizobium meliloti

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