Bystander hyperactivation of preimmune CD8+ T cells in chronic HCV patients
Chronic infection perturbs immune homeostasis. While prior studies have reported dysregulation of effector and memory cells, little is known about the effects on naïve T cell populations. We performed a cross-sectional study of chronic hepatitis C (cHCV) patients using tetramer-associated magnetic e...
Main Authors: | Cécile Alanio, Francesco Nicoli, Philippe Sultanik, Tobias Flecken, Brieuc Perot, Darragh Duffy, Elisabetta Bianchi, Annick Lim, Emmanuel Clave, Marit M van Buuren, Aurélie Schnuriger, Kerstin Johnsson, Jeremy Boussier, Antoine Garbarg-Chenon, Laurence Bousquet, Estelle Mottez, Ton N Schumacher, Antoine Toubert, Victor Appay, Farhad Heshmati, Robert Thimme, Stanislas Pol, Vincent Mallet, Matthew L Albert |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-11-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/07916 |
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