Investigation on Plasmodium falciparum and Plasmodium vivax Infection Influencing Host Haematological Factors in Tribal Dominant and Malaria Endemic Population of Jharkhand

The study was undertaken to elucidate the association of host haematological and biochemical indices in P.falciparum and P.vivax malaria in order to explore whether these parameters are unique to disease or act as potential diagnostic marker. Haematological and biochemical parameters in 106 malar...

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Bibliographic Details
Main Authors: Mohammad Raziuddin, Mohammad Mobassir Hussain, Mohammad Sohail, Kumar Abhishek
Format: Article
Language:English
Published: PAGEPress Publications 2014-08-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Subjects:
Online Access:https://mjhid.org/index.php/mjhid/article/view/1715
Description
Summary:The study was undertaken to elucidate the association of host haematological and biochemical indices in P.falciparum and P.vivax malaria in order to explore whether these parameters are unique to disease or act as potential diagnostic marker. Haematological and biochemical parameters in 106 malaria patients and 33 healthy subjects were evaluated. Following parameters were significantly lower in all infection types (P.vivax, P.falciparum and Mixed Infection); haemoglobin, blood sugar, PCV and blood urea, while ESR is significantly higher in all types of infection whereas serum bilirubin and creatinine are significantly higher except mixed and vivax infection respectively. Interestingly, parasitemia, temperature and age are significantly correlated with blood urea, blood sugar and ESR respectively in vivax infection whereas parasitemia with PCV and blood sugar and age with PCV in falciparum infection. These evaluations may be considered to be reliable and possess promising rational for improved diagnostic in combination with other clinical parameters during malaria infection.
ISSN:2035-3006